I have been using estrace cream for about 2 in a half weeks.. My Doctor told me to avoid having sex for a week, 1 week after starting the estrace cream my husband and I has had intercourse a few times.. if he is having side effects from this what kind of side effects would they be? My husband has complained of irritation like a funny feeling a burning sensation on his penis. Is this because he's having a reaction to the estrogen that was meant for me?