I have recently discovered I'm allergic to an antibiotic that was prescribed to me. The doctor then prescribed 40mg of Prednisone for one week, and 20mg the following week, along with Benadryl and Pepcid. I have been taking all this medication for three days now and barely see any improvement on the rash and hives on my skin. I have been reading up on the side effects of Prednisone and am wondering if I could just allow my skin to clear naturally with the aid of Benadryl.