Viibryd worked great but is not available where I'm moving to so I'm trying a med that is available. I took 5 mg of Trintellix and 10 mg Viibryd the 1st week. I experienced withdrawal symptoms from the lower dose of Viibryd and nothing positive from the 5 mg of Trintellix. Now I'm in week 2 (day 3) where I'm taking no Viibryd and 10 mg of Trintellix. My mood is down and my anxiety is up and I am becoming inpatient with this little experiment. Should I give the Trintellix more time? If so, how much more time? This is frustrating when I know I can get relief in a matter of days by going back to 20 mg Viibryd.
Day 10 on Trintellix and nothing but pain. I'm switching from 20 mg Viibryd to 10 mg Trintellix.
Question posted by Rathmullan on 11 Nov 2021
Last updated on 11 November 2021
Answers
WildcatVet
11 Nov 2021
Hi, Rathmullan!
Depression and anxiety can be symptoms of discontinuation and the length of time they last depends on several factors including your dose, the length of time you took it, and your personal metabolism... it can often take weeks for them to subside. Could this be part of the problem?
Couple that with starting an antidepressant can often cause temporary new/increased depression, mood lability, and anxiety that can last for several weeks.
The top section of this link is from the literature here on Drugs.com about when you can expect improvement from Trintellix:
https://www.drugs.com/medical-answers/long-trintellix-start-working-3539533/
I would think that essence of time will resolve your issues. It's hard not to be impatient because we all want to feel better fast but you know these drugs don't work that way.
Stay positive and let your metabolism stabilize. You've been in long enough that you should see results very quickly now.
Best regards and hang in there. As they say, "The best is yet to come".
Wildcat
Rathmullan
11 Nov 2021
Thank You WCV for your encouraging response!
I know that everything you've said in your response is true. It's just that when, what I'm experiencing, is in some sense self inflicted it's hard to be patient. I know I can return to Viibryd and start to feel better again whereas there is no guarantee that Trintellix will work for me. In the latter case, I guess the one benefit I can count on, should I continue the Trintellix is knowing whether or not it works for me.
The last 8 days have felt like "days lost" to me. But I will try, one day at a time, to hang in there another 11 days at 10 mg before concluding whether or not Trintellix is an option.
Take care for now and THANK YOU again!
WildcatVet
11 Nov 2021
You're more than welcome! Please let us know how you do.
WC
Klonopinkid
11 Nov 2021
Trintellix took 5 weeks at 5mg for me to start working. I also recommend ginger chews from the ginger people to get over the nausea if you get it. I'd think
Viibryd would take sometime getting over the withdrawals. Never taken it though.
Rathmullan
11 Nov 2021
Thank You Klonopinkid. Your response is encouraging. I guess I need to tone down my expectations. I was thinking that because Viibryd and Trintellix share certain attributes that maybe the latter would start working faster for me. Too, I remember starting to feel the benefits of Viibryd about 5 or 6 days into 20 mg (that was after 1 week at 10 mg of Viibryd).
Both the Viibryd withdrawal and Trintellix nausea are contributing to my impatience. I will dial back my expectations on the anticipated timing of improvement from Trintellix.
Take care for now and Thanks again.
Related topics
depression, withdrawal, viibryd, symptom, trintellix
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