Bupropion - Does anyone notice much of a difference between 150mg and 300mg/day for extended?

Hi Allison: I took 150 mg Bupropion Sr successfully for years to relieve my anxiety. Whenever I went to 150mg twice a day of Bupropion Sr, I would get increased anxiety, it would affect my sleep patterns, cause me constipation and other problems. At 150 mgs, I was calm, focused, motivated, and could function so much better, for years, actually, at this dose.

Hi Allison: I did well on 150mg Bupropion SR once a day. Whenever I went to 150mg twice a day (300mg), I had problems with constipation, irritability, increased anxiety, stomach upset, and other problems. I could function much better at 150 mg a day of bupropion sr, for years, as a matter of fact. It kept me calm, focused, gave me motivation, and kept me from depression at that dose.

I took 150 mg for 2 yrs. they upped it to 300 mg. Didn’t really tell the difference. I had to go to a different dr. He told me I had been over medicated for years. He cut me back to 150 mg getting off that one pill was terrible. The withdrawals were horrific ! He should have weened me off it ! Just be careful !