Started Apriso 30 days ago. I have pancolitis and had been taking Asacol for 20 yrs and medicare stopped paying for this medication. I switched to Apriso and am wondering about abdominal swelling. is this a side effect? One thing I have noticed is that the awful pain I had in knees, etc. is no longer bothering me. I get up in the morning and have no arthritic pain and I hope it is because of the Asacl. The abdominal swelling is bothering me however.