I am recently recovering from alcohol dependance and am currently taking disulfiram 200mg a day. I have also used benzos in the past mainly diazepam but not with alcohol. I have no desire to drink but have started using diazepam again about average 40mg a day, usually 2 in the morning and 2 in the evening. i have been told of the dangers and horrors of withdrawl and want to stop using them. I have been to my community drugs team and they are going to suggest a rate to taper me off them. But i am worried is there any danger of interaction with disulfuram (antabuse) with diazepam. I am going to speak to my doctor this week. But i am also scared if i ask the alcohol unit i attend that they may cut me off my antabuse and i end drinking again. So can anyone tell me is ther any serious risks or dangers of mixing valium and antabuse?
Responses (1)
maso41695 Aug 2010
Hi,
Interactions between your selected drugs
diazepam ↔ disulfiram
Applies to: Valium (diazepam), Antabuse (disulfiram)
ADJUST DOSE: The combination of disulfiram and benzodiazepines may increase CNS depression. The mechanism may relate to the inhibition of hepatic oxidation of benzodiazepines by disulfiram. Diazepam and chlordiazepoxide may interact with disulfiram to a greater extent than other benzodiazepines. However, the interaction has also been reported with temazepam, even though it is metabolized by glucuronidation.
MANAGEMENT: The benzodiazepine dosage may require reduction. Patients should be monitored for excessive and prolonged sedation.
Read more: http://www.drugs.com/interactions-check.php?drug_list=917-482,862-441#ixzz0vgwrvUvh
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.
Similar questions
I drank yesterday. Am I able to start antabuse today or not?
since there is alcohol in my blood stream since I drank yesterday, would there be a problem (would I get really sick) if i started antabuse or ...
2 answers • 19 Apr 2010 • 
Can you use skin products with denatured alcohol content while on Disulfiram?
1 answer • 10 Aug 2010 •
I am due to start taking antabuse in 3 days time. I am aware of the dangerous side efects?
very worried about which products i can and can not use..ie: facial wipes and hair products..like highlighting kits.also cleaning products with ...
1 answer • 29 Nov 2010 •
Antabuse - is anyone experienced with this medication?
My friend started drinking 26 hours after taking her last tablet and is now experiencing hyperthermia and flushed face and the onset of a headache ...
1 answer • 7 Jan 2011 •
Disulfiram - 10 days on antabuse?
I have been drinking since 17 and am 40 now. I started antabuse 10 days ago and crave alcohal like crazy. I'm thinking of going off and having ...
1 answer • 6 Dec 2011 •