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Can I take amoxicillin if allergic to ceclor?

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Mike070519 5 July 2019

I realize this is an old question, but since the only other answer includes definitely incorrect information, I wanted to at least correct that misstatement, and have included further information I think is relevant. I'm not any kind of health care professional, but since I did have a reaction to Ceclor myself, I have spoken to a couple of doctors about the issue and once drug-related information became readily available on the Internet, I did further research myself.

First and foremost, Ceclor and amoxicillin are NOT in the same class/family. Ceclor is a second-generation cephalosporins [sorry about the incorrect plural, for some reason this site refuses to let me post the singular and keeps "autocorrecting" it to the plural). Amoxicillin on the other hand is in the penicillin family. Secondly, it's also worth pointing out that Ceclor has a relatively high rate of adverse reactions compared to later cephalosporins. (I'm not any kind of health care professional, but I think they're up a fourth- or fifth "generation" at this point, with the later generations generally tending to result in fewer adverse reactions than the earlier ones.) So this particular instance of cross-sensitivity is a little different than many other situations involving potential cross-sensitivities between unrelated medications.

There is _some_ cross-sensitivity between Ceclor and amoxicillin, but it's not equal in both directions. If you're hypersensitive to amoxicillin or other penicillin family antibiotics, there is a somewhat greater chance of a negative reaction to Ceclor than the other way around. But the last time I looked into it in any real detail, the incidence of cross-sensitivity was at most 10% in either case.

I would be sure to advise your health care professionals that you had a reaction to Ceclor, but I would not be overly concerned about taking amoxicillin due only to a one-time reaction to Ceclor. without other reason to believe you are or may be allergic penicillin-class antibiotics.

Lastly, while anecdotal "evidence" isn't really worth anything as real evidence, by way of personal illustration, I will mention that I myself had a somewhat atypical, though definite, histamine-mediated reaction to Ceclor (what was atypical was that the reaction set in only after I had completed the full course of Ceclor and I didn't develop a rash per se, but I did have patches of unraised red skin - looked a bit like a a bad sunburn - and experienced intense itchiness literally from my scalp to the soles of my feet for a couple of days on end until I started taking an antihistamine). But in the 25 years since I reacted to the Ceclor, I have taken several different penicillin-class antibiotics - including both plain amoxicillin and Augmentin, and Penicillin V itself - a number of times without the slightest hint of a reaction to any of the -cillins.

Votes: +0
chuck1957 31 Jan 2016

danika86; these 2 drugs are in the same family.ready this.((Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.)) But it depends on what type of reaction you had from the AMOXIL. they are in the same family did you tell your doctor you had an allergy to Amoxil I WOULD NOT TAKE IT and call your pharmacist and double check today. But depending on the allergic reaction, you could get the same thing. So you have to make sure you always tell the doctor of this allergy and also by using one pharmacy and they have your allergies on file in the computer it should have caught this.So to be safe wait until Monday and call your doctor.

Votes: +0
Mike070519 5 July 2019

Ceclor and amoxicillin are not in the same class/family of antibiotics. There is some cross-sensitivity between the two, but they're fundamentally different both chemically and medically/physiologically. (They both work against some bacteria, but in general they're coverage is not coextensive.)

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ceclor, allergic reactions, bronchitis, amoxicillin

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