I heard that the MYLAN brand is the best do to the size and adhesive properties. I also heard that the SANDOZ brand is exactly the same as the brand name Duragesic. Any help would be appreciated! Thanks!
What's the best generic Fentanyl Patch? SANDOZ? MYLAN?
Question posted by mitjason on 19 Dec 2009
Last updated on 6 April 2021 by oderus66
34 Answers
Sandoz by far. It contains the most fentanyl and it sticks well. I still use the overlays which I get online.
The answer is subjective when comparing 2 drugs in the same category. Some will swear by Mylan and some by Sandoz. As Caligirl mentioned the only way you would know the difference is if you tried both as she has. Not all manufacturers formulation are across the board. Additionally contrary to popular belief that generic is the same as brand name. This is false. They are not equal to each other. In fact there are some people that can not tolerate the generic version and they can only take the brand name such as several of my customers at the pharmacy. There is a reason why generic is substantially cheaper than brand name. -- Pharmacist in Dallas
So to the person that posted about losing her sister to Sandoz brand, I am so sorry. I have tried & tried to speak to the pharmacist & my doctor about the issues with different manufacturers. Here is what is crazy! The active ingredient (fentanyl) is different! Yes the sizes of the patches are different but should have no relevance. The total amount of active ingredient should be the same. Sandoz has the highest amount as does Duragesic “the brand”. I am on the 50’s and have been for 10 years. Here is a breakdown:
Alvogen 18.88 cm/2. 5.32/mg of fentanyl
Mylan 12.5 cm/2 5.10/mg of fentanyl
Janssen&Sandoz 21/cm2 8.4/mg fentanyl
Mallinckrot size 19/cm2 5.5mg/fentanyl
Apotex 21.4/cm2 5.52mg fentanyl
Always look on the outside of the box and it will tell you how much of the “active” ingredient there is. Sandoz and the brand names discontinued all fentanyl patches probably for this reason. My pharmacy would only fill my pan so I went through sever withdrawals. I hope this helps you guys!
I have taken fentanyl 100 mcg Mylan patches for 11 years, they are Dr. ordered and the Best!!
I know it is almost a decade from the original post but the issue is still relevant. Since Sandoz no longer manufactures patches I now use Alvogen. I am allergic to most adhesives. The best patch for my pain is Watson/Actavis but for my skin Sandoz was the best. Alvogen is the best alternative for me but are not as good at pain control as Watson or Sandoz. The Albigensian do not give me even 48 hours of pain control but they do not blister my skin, which is an important consideration. I still manage to sweat off more than a couple a month. Until the DEA got really involved in telling my doctor how much medication I need and when to change patches, I had the ability to replace patches that did not adhere well or that were irritating. I am also being forced to reduce the dose that worked dry well for me for 2 decades because the government knows best. I hate that a recommendation from the CDC was treated as an edict by many state governments.
This recommendation was not intended for long term pain patients who have been on opiates for years. Now was it intended for people who have genetic issues which make doses that would be very high for MOST people but are barely effective for ultra rapid metabolizers.
The short answer is that no one patch is the best for everyone. I have found that as for effectiveness, the amount of fentanyl patch determines which works best on my pain. The higher the amount of fentanyl, the better the pain Co Tyrol. If adhesive allergies weren’t an issue I would use Watson/Activis. Since adhesives are an issue for me I use the one that harms my skin the least. Other people can give you guidance but only your body can select which is the best for you. Skin differences, allergies and rate of opiate metabolism are just some of the factors you must take into consideration.
I forgot to mention, depending on your dose if you are using more than one and start to feel dizzy, it means you are getting too much. It can be because you are doing nothing when normally you are somewhat active. If and when it happens to me I remove one 50 mcg patch and am ok within 20 min. but if I start doing things again and hurting I reuse the one I removed. As long as you stick it to plastic that it will peel off after it can be reused. Sometimes just moistening the location helps or the No No clean area with rubbing alcohol and placing it on while still a bit moist.
Over the past 20 years I've tried most of them and by far Teva and Mylan are the best for pain control and staying on after you put them on. They are both Matrix patches but Mylan has about half the Fentanyl in them but every other brand still has half the Fentanyl on them when you take them off where Mylan only has a bit. You still get the same amount in your body though. I stick with Teva since once on they stay on especially if your body gets used to having them in the same place each time. I place mine on the front of my upper leg where my skin is tight and flat and have no issues at all.
Sandoz has discontinued their fentanyl patches. I called the company today and was given the bad news. I’ve relied on their patches for pain control for years. I’m currently using Mallincrodt patches and not doing well. I’m trying to research which patches are most similar to the Sandoz. Any input would be much appreciated.
I've used their patches for years as well and also called them. There are no other brands that compare to them unfortunately, in many respects. Good luck to us both.
I just discovered this too... and Sandoz is the only brand I will use, period... But I have GREAT news for you... I recently tried the 100 MCG brand - it's identical to the Sandoz (matrix style, same amount of active Fent being released, I truly can say that if I were to put on this patch without knowing it was NOT Sandoz brand, I would be shocked, because I could not tell a difference at all, they worked WONDERFULLY... the brand is called ALVOGEN... look it up, I promise you, it is the closest thing you will find to Sandoz... I have been on Sandoz patches for 11 years now... but as long as this new manufact, is around, ALVOGEN is the ONE TO GET!!! LET ME KNOW if u are able to get them!!! and if u feel like they worked the same as Sandoz!!!
I would suggest to anyone that uses the sandoz brand to not. it has overdosed ppl. including my sister who is now dead. and they have lawsuits against this brand.
we used to always try to get this brand because it worked good. but death was the price I paid for or. I told my pharmacy to makr5sure I never get this brand.
you can look it up and find out that this brand has lawsuits from overdosing ppl.
I would suggest that u never get sandoz brand. for 1 my sister died of overdose from this brand as has many others. they have lawsuits about this brand. we use to always try and get this brand and the price I paid was my sister. if u don't believe me do some research on this brand it has overdosed others
I have not been able to get. Watson, or par brand patches the only ones that works. But my doctor wrote me a script for either par or watson and told me that he was going out of business. His company was bought out and told him that they are closing up his office. So now not only can I not get the right patches but I can't go to my pain doctor and get something else. After 10 plus years on 100 mcg. Anyone know what to do. I think that the pharmaceutical companies should be held accountable for us not being able to get the proper medicine prescribed for us. What do you think.
I'm a medical rep and it all goes down to insurance companies and the pharmacy. What even they have contract with is what you get.
I've been on mylan for almost a year and I'm having g problems keeping them on now that hotter weather is here. They tend to itch a lot I'm using reader overlay and mylan overlays the company sends for free I'm wanting to try this other so if you do get to try Sandoz Please inform if you have any problems I can say Mylan does work good but maybe it's me post menopausal why I'm having trouble I think with either one you will get a little quality of life back O didn't want at first but Mylan brand has been a God send.
I was switched from branded Duragesic to generic Mylan fentanyl and went through withdrawal. It was horrible. All the muscles in my body ached.
I just found out that my pharmacy no longer carries 25 mcg Actavis brand and I had to get Mylan brand. They said that there was a recall of all Actavis patches. I can not find anything thing on the internet about a recall.
They gave me Mylan brand early last year for one month and they did not work well at all. I had to take twice as much breakthrough medication. I have been designating Actavis ever since, but now it looks like they are no longer available. I tried Walgreens, CVS and Fry's and none of them carry it anymore. I am thinking that because they are the gel and easier to abuse that pharmacies don't want to carry them. I wish I could find a pharmacy in Phoenix, AZ that carries Actavis because I would take my next prescription there. It is too bad there is no way to search that on the internet. If anyone know of a pharmacy that carries Actavis please post.
p.s. I found this out on Walgreens site: Do not switch brands of this drug unless you talk with your doctor. It was Walgreens who won't order the Actavis for me anymore, how ironic.
Watson / Actavis has recalled ALL fentanyl patches. There was a problem of degeneration, I believe. My best friend has been on them for years... and had to switch to Mylan. She went thru massive withdrawal. I am trying ting to find a pharmacy that carries Sandoz for her. Do you know how I could do this? Thx for any info!
I was on Actavis and it worked wonderfully. Then Walgreens switched to brand Mallinckrodt. Horrible reactions with BP. Pain level was effective. Spoke to Walgreens pharmacist and he said “Walgreens cannot choose the brand they receive”!!! Now, I cannot find a pharmacy that carries Actavis. Oh, I have to call each pharmacy too! Living in Houston, this is alot of calls.
***I just found this site and have really learned a lot!!
I am having the same issue in Phoenix, AZ. I spoke with my pain doctor today and she said she can write in a brand even though I can't request it, she can. I haven't tried it yet, but will next month. My prescription was already written this month. I'll tell you if it works. The bad part is, if it isn't in stock, they'll need to order. Have you found any place yet?
I have found that the matrix type patch causes a bad chemical burn on my skin. The patches with the gel are not as bad. They are however so hard to get. It seems with the government regulations that we cannot drop off the prescription until we need it, and then the pharmacies don't have them. The problem then is that we are out there going through withdrawal while the health care companies decide to pay for the prescription or the pharmacy can REMEMBER that you get this every month. I had a young friend die when she could not refill her prescription so be very careful.
Sorry I have gone off on another topic.
Related topics
duragesic, pain, fentanyl, breakthrough pain
Further information
Similar questions
Search for questions
Still looking for answers? Try searching for what you seek or ask your own question.