How to transition to Invega Hayfera from Invega Trinza or Invega Sustenna?
Before transitioning to Invega Hayfera, a person must have been administered Invega Sustenna for at least 4 months or Invega Trinza for at least one three-month cycle and tolerated either of them well.
Switching from Invega Sustenna to Invega Hayfera
For a seamless transition, it is recommended that the last two doses of Invega Sustenna are the same dosage strength. Start Invega Hayfera up to 7 days before, on, or 7 days after the day the next 1-month Invega Sustenna dose was due. The following dosage guide is recommended by the manufacturer:
- If the last dose of Invega Sustenna was 156 mg, then initiate Invega Hayfera at 1092 mg
- If the last dose of Invega Sustenna was 234 mg, then initiate Invega Hayfera at 1560 mg.
Invega Hafyera should be administered once every 6 months by a health care professional into either the deltoid muscle of the arm or the gluteal muscle of the buttocks.
Switching from Invega Trinza to Invega Hayfera
Start Invega Hayfera up to 2 weeks before, on, or 2 weeks after the next 3-monthly Invega Trinza dose was due. The following dosage guide is recommended by the manufacturer:
- If the last dose of Invega Trinza was 546 mg, then initiate Invega Hayfera at 1092 mg
- If the last dose of Invega Trinza was 819 mg, then initiate Invega Hayfera at 1560 mg.
Invega Hafyera should be administered once every 6 months by a health care professional into either the deltoid muscle of the arm or the gluteal muscle of the buttocks.
References
- Invega Sustenna (paliperidone palmitate). Updated 08/2021. Janssen Pharmaceuticals, Inc. https://www.drugs.com/pro/invega-sustenna.html
- Invega Trinza (paliperidone palmitate). Updated 08/2021. Janssen Pharmaceuticals, Inc. https://www.drugs.com/pro/invega-trinza.html#s-34069-5
- Invega Hafyera. (paliperidone palmitate). Updated 09/2021. Janssen Pharmaceuticals, Inc.
- https://www.drugs.com/pro/invega-hafyera.html#s-34069-5
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