How many doses of Arexvy are required?

Just one shot of Arexvy into the deltoid muscle of the upper arm is needed to protect older adults against lower respiratory tract disease (LRTD) caused by the respiratory syncytial virus (RSV). RSV season usually begins in October in the U.S., and people should get their shot before it starts. It is safe to get at the same time as a flu shot.

It is not yet known if Arexvy will need to be given every year, like the flu shot. RSV does not mutate in the same way as influenza and SARS-CoV-2 do, so there shouldn’t be a need to update the vaccine or re-dose people every year, but more research is needed. Clinical trials reported protection for two RSV seasons, so it may only need to be given every two years.

Arexvy is approved for the prevention of LRTD caused by RSV in adults aged:

• 60 years of age and older
• 50 through 59 years of age who are at increased risk for LRTD caused by RSV because of chronic medical conditions such as chronic pulmonary disease, chronic cardiovascular disease, diabetes, chronic kidney or liver disease.