Low Substituted Hydroxypropyl Cellulose
Medically reviewed by Drugs.com. Last updated on Mar 15, 2024.
Excipient (pharmacologically inactive substance)
What is it?
Low substituted hydroxypropyl cellulose, also commonly known as hydroxypropyl methycellulose (HPMC) or hypromellose is a binder and disintegrant inactive ingredient for solid dose forms in the pharmaceutical industry. As a powder, hypromellose is off-white to beige and may be in granules.
Hypromellose is considered an inert ingredient. Hydroxypropyl cellulose is soluble in both water and alcohol, but low substituted hydroxypropyl cellulose swells in water and is insoluble.
Hydroxypropyl methycellulose is also a coating agent and film-former used as an inactive ingredient in the pharmaceutical industry.[1] It has also been used as a rate-controlling polymer for sustained-release dose forms.
List of medications using Low Substituted Hydroxypropyl Cellulose
- Bupropion Hydrochloride Extended-Release (XL) 150 mg
- Bupropion Hydrochloride Extended-Release (XL) 300 mg
- Clopidogrel Bisulfate 75 mg (base)
- Entresto sacubitril 24 mg / valsartan 26 mg
- Losartan Potassium 25 mg
- Losartan Potassium 100 mg
- Losartan Potassium 50 mg
- Methocarbamol 500 mg
- Methocarbamol 750 mg
- Methocarbamol 500 mg
- Methocarbamol 750 mg
- Metronidazole 500 mg
- Metronidazole 500 mg
- Mirtazapine 15 mg
- Mirtazapine 7.5 mg
- Mirtazapine 45 mg
- Mirtazapine 30 mg
- Omeprazole Delayed Release 20 mg
- Promethazine Hydrochloride 12.5 mg
- Promethazine Hydrochloride 25 mg
References
- Dave RH. Overview of pharmaceutical excipients used in tablets and capsules. Drug Topics (online). Advanstar. 10/24/2008 http://drugtopics.modernmedicine.com/drugtopics/Top+News/Overview-of-pharmaceutical-excipients-used-in-tabl/ArticleStandard/Article/detail/561047. Accessed 08/19/2011
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
