Cotrim Interactions
There are 412 drugs known to interact with Cotrim (sulfamethoxazole/trimethoprim), along with 12 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 61 are major, 146 are moderate, and 205 are minor.
- View all 412 medications that may interact with Cotrim
- View Cotrim alcohol/food interactions (1)
- View Cotrim disease interactions (12)
Most frequently checked interactions
View interaction reports for Cotrim (sulfamethoxazole / trimethoprim) and the medicines listed below.
- acyclovir
- allopurinol
- amikacin
- amlodipine
- amoxicillin
- amoxicillin / clavulanate
- attapulgite
- azithromycin
- ceftriaxone
- cetirizine
- ciprofloxacin
- clindamycin
- doxycycline
- ethambutol
- fentanyl
- fluconazole
- furosemide
- ibuprofen
- levofloxacin
- meropenem
- methylprednisolone
- metronidazole
- omeprazole
- Paracetamol (acetaminophen)
- streptomycin
- vancomycin
- Vitamin B1 (thiamine)
- Vitamin B12 (cyanocobalamin)
- Vitamin B6 (pyridoxine)
- vitamin e
Cotrim alcohol/food interactions
There is 1 alcohol/food interaction with Cotrim (sulfamethoxazole / trimethoprim).
Cotrim disease interactions
There are 12 disease interactions with Cotrim (sulfamethoxazole / trimethoprim) which include:
- colitis
- hematologic toxicity
- hypersensitivity reactions
- liver disease
- porphyria
- renal dysfunction
- folate deficiency
- crystalluria
- hemodialysis
- urinary obstruction
- dialysis
- renal dysfunction
More about Cotrim (sulfamethoxazole / trimethoprim)
- Cotrim consumer information
- Compare alternatives
- Imprints, shape & color data
- Side effects
- Dosage information
- During pregnancy
- Drug class: sulfonamides
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.