Comparing Epiduo vs Spironolactone
Epiduo | Spironolactone |
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Epiduo (adapalene / benzoyl peroxide) | Spironolactone |
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Prescription only
Prescribed for Acne. Epiduo may also be used for purposes not listed in this medication guide. |
Prescription only
Spironolactone is a diuretic that may be used to remove excess fluid (edema) from the body, lower blood pressure, or treat hyperaldosteronism. It does not cause potassium loss from the body; however... View more |
Related suggestions |
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More about Epiduo (adapalene / benzoyl peroxide) | More about Spironolactone | ||||||||||||||||
Ratings & Reviews | |||||||||||||||||
Epiduo has an average rating of 7.3 out of 10 from a total of 722 ratings on Drugs.com. 65% of reviewers reported a positive effect, while 17% reported a negative effect. |
Spironolactone has an average rating of 6.9 out of 10 from a total of 693 ratings on Drugs.com. 59% of reviewers reported a positive effect, while 25% reported a negative effect. |
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Drug Class | |||||||||||||||||
Side Effects | |||||||||||||||||
See also: Epiduo side effects in more detail. |
See also: spironolactone side effects in more detail. |
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Generic Availability | |||||||||||||||||
Lower cost generic |
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Pricing and Coupons * Prices are without insurance | |||||||||||||||||
View all Epiduo prices |
View all spironolactone prices |
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Dosage Form(s) Available | |||||||||||||||||
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Brand Names | |||||||||||||||||
Other adapalene / benzoyl peroxide brands include: Epiduo Forte | Aldactone, CaroSpir | ||||||||||||||||
Half Life The half-life of a drug is the time taken for the plasma concentration of a drug to reduce to half its original value. | |||||||||||||||||
51 hours |
37 hours |
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CSA Schedule ** View glossary of terms | |||||||||||||||||
Not a controlled drug
Is not subject to the Controlled Substances Act. |
Not a controlled drug
Is not subject to the Controlled Substances Act. |
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Pregnancy Category | |||||||||||||||||
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
Category C
Risk cannot be ruled out
See the full pregnancy warnings document. |
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Drug Interactions | |||||||||||||||||
A total of 17 drugs are known to interact with Epiduo:
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A total of 382 drugs are known to interact with spironolactone:
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Alcohol/Food/Lifestyle Interactions | |||||||||||||||||
No known alcohol/food interactions. This does not necessarily mean no interactions exist. Always consult your healthcare provider. |
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Disease Interactions | |||||||||||||||||
First Approval Date | |||||||||||||||||
December 08, 2008 |
January 21, 1960 |
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WADA Class View World Anti-Doping Agency classifications. | |||||||||||||||||
N/A |
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More Information | |||||||||||||||||
Patient resources | |||||||||||||||||
Professional Resources | |||||||||||||||||
Related Treatment Guide | |||||||||||||||||
** The Controlled Substances Act (CSA) schedule information displayed applies to substances regulated under federal law. There may be variations in CSA schedules between individual states.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.