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Miconazole topical Pregnancy and Breastfeeding Warnings

Brand names: Absorbine Antifungal Foot Powder, Azolen, Baza Antifungal, Critic-Aid Clear AF, Cruex Prescription Strength, Dermagran AF, Desenex AF, Lotrimin AF Athlete's Foot Powder, Lotrimin AF Athlete's Foot Powder Spray, Lotrimin AF Athlete's Foot Spray, Lotrimin AF Jock Itch Powder Spray, Micatin, Micatin Liquid Foot, Micon 7, Miranel AF, Mitrazol, Monistat, Monistat 1 Combination Pack, Monistat 3, Monistat 7, Monistat-Derm, NuZole, Vagistat-3, Zeasorb-AF, Zeasorb-AF Jock Itch

Medically reviewed by Drugs.com. Last updated on Jul 28, 2023.

Miconazole topical Pregnancy Warnings

Miconazole has not officially been assigned to a pregnancy category by the FDA. In clinical trials, miconazole treatment of vaginal candidiasis has not been associated with fetal harm. Miconazole is only recommended for use during pregnancy when there are no alternatives and benefit outweighs risk.

Pregnancy predisposes patients to the development of vaginal candidiasis due to changes in the vaginal tract. Miconazole has been used in several clinical trials for the treatment of vaginal candidiasis, generally during the second and third trimester, without evidence of fetal harm.

In a review of 229,101 deliveries to Michigan Medicaid patients, 7266 first-trimester exposures to miconazole and 31,503 exposures any time during pregnancy were recorded. A total of 304 birth defects were reported with first trimester exposure (273 expected) and included (observed/expected) 77/73 cardiovascular defects, 14/13 clefts, 3 spina bifida, 4/4 oral clefts, 22/15 polydactyly, 12/9 limb reductions, and 20/17 hypospadias (written communication, Franz Rosa, MD, Food and Drug Administration, 1994). These data do not support an association between first-trimester miconazole use and birth defects.

See references

Miconazole topical Breastfeeding Warnings

There are no data on the excretion of miconazole into human milk.

See references

See also

References for pregnancy information

  1. Weisberg M (1986) "Treatment of vaginal candidiasis in pregnant women." Clin Ther, 8, p. 563-7
  2. "Product Information. Monistat 7 (miconazole topical)." Ortho McNeil Pharmaceutical

References for breastfeeding information

  1. "Product Information. Monistat 7 (miconazole topical)." Ortho McNeil Pharmaceutical

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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