... be hereditary? Wondering for the sake of my daughters. My second question is about medication for UTI's. I get them often, and as I'm sure many of you know, they are quite easy to self diagnose. So, my Dr gave me a prescription for Macrobid to keep on hand to take 1 after intercourse or to take 2 for 5 days if I don't catch it in time and get a full blown UTI. I ran out of that prescription and had to switch Dr's. The new Dr also gave me a prescription to take the same way but instead of Macrobid she gave me Bactrim ds. I took it about 4 times with no issues but the 5th time I started itching like crazy and my eyelids swelled up. My friend that is a nurse told me to take Benadryl. I took the Benadryl and soon after the swelling and intense itching subsided. I can only assume I had an allergic reaction to the Bactrim. Can you develop an allergic reaction to a medication you have taken before with no problems? It helped with the oncoming feelings and signs of a UTI but because of the effect I had, I definitely don't want to take the Bactrim again so I called my Dr to see about getting a prescription for Macrobid again. I am now with a different Dr (again) due to the last one leaving the practice. This new Dr said she didn't like to give out antibiotics just to "have on hand" and would like me to come in and be seen whenever I have a UTI. I'm a little frustrated with this as I get UTI's so often and it really helps to just take 1 after intercourse. Plus, because they are SO painful I'd rather not wait until I got one and had to be seen. Especially since it is very difficult to get into my Dr for a same day appt. Lastly, the cost of going in every time would be ridiculous. Does anyone have any suggestions for my situation? Any advice would be much appreciated. Thanks!