Generic Name: olanzapine (extended release injectable suspension) (oh LAN za peen)
Brand Names: ZyPREXA Relprevv
What is Zyprexa Relprevv?
Zyprexa Relprevv (olanzapine) is an antipsychotic medication that affects chemicals in the brain.
Zyprexa Relprevv is an extended release injectable suspension used to treat adults who are in an agitated state due to schizophrenia or bipolar disorder (manic depression). Zyprexa Relprevv is not for daily use to treat any psychotic condition.
Zyprexa Relprevv may also be used for purposes not listed in this medication guide.
You should not receive Zyprexa Relprevv if you are allergic to olanzapine.
Before you receive Zyprexa Relprevv, tell your doctor if you have heart disease, congestive heart failure, a heart rhythm disorder, a history of heart attack or stroke, or if you are also using a sedative such as Valium.
You may need to stop breast-feeding after receiving an Zyprexa Relprevv. Talk to your doctor about the best way to feed your baby if you take Zyprexa Relprevv.
In an emergency situation it may not be possible before you are treated to tell your caregivers about your health conditions or if you are pregnant or breast feeding. Make sure any doctor caring for you afterward knows that you have received this medicine.
Olanzapine may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert.
Before receiving Zyprexa Relprevv
Zyprexa Relprevv is not for use in psychotic conditions related to dementia. Olanzapine may cause heart failure, sudden death, or pneumonia in older adults with dementia-related conditions. You should not receive Zyprexa Relprevv if you are allergic to olanzapine.
If possible before you receive Zyprexa Relprevv, tell your doctor if you have:
congestive heart failure;
a heart rhythm disorder;
a history of heart attack or stroke; or
if you are also using a sedative such as Valium.
FDA pregnancy category C. It is not known whether Zyprexa Relprevv will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant while using this medication. Olanzapine can pass into breast milk and may harm a nursing baby. You will need to stop breast-feeding after receiving Zyprexa Relprevv. Talk to your octor about the best way to feed your baby if you take Zyprexa Relprevv. In an emergency situation, it may not be possible before you are treated with olanzapine to tell your caregivers if you are pregnant or breast feeding. Make sure any doctor caring for your pregnancy or your baby knows you have received this medicine.
See also: Pregnancy and breastfeeding warnings (in more detail)
How is Zyprexa Relprevv given?
Zyprexa Relprevv is injected into the muscle in your buttock (gluteus). You will receive this injection in a clinic or hospital setting.
After receiving Zyprexa Relprevv, you will need to stay at the clinic for at least 3 hours. When you leave the clinic, someone must be with you.
You should not drive or use heavy machinery for the rest of the day after receiving Zyprexa Relprevv.
Be aware that there are two Zyprexa intramuscular injections with different doses. Zyprexa intramuscular injection is a short-acting formulation and should not be confused with Zyprexa Relprevv.
What happens if I miss a dose?
Since Zyprexa Relprevv is given by a healthcare professional in an emergency setting, you are not likely to miss a dose.
What happens if I overdose?
Since Zyprexa Relprevv is given by a healthcare professional in a medical setting, an overdose is unlikely to occur.
What should I avoid?
Olanzapine may impair your thinking or reactions. Be careful if you do anything that requires you to be alert.
Avoid getting up too fast from a sitting or lying position, or you may feel dizzy. Get up slowly and steady yourself to prevent a fall.
Drinking alcohol can increase sleepiness caused by olanzapine.
Zyprexa Relprevv side effects
Get emergency medical help if you have any of these signs of an allergic reaction to Zyprexa Relprevv: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.
Tell your caregivers at once if you have a serious side effect such as:
fast or slow heart rate;
feeling like you might pass out;
twitching or uncontrollable movements of your eyes, lips, tongue, face, arms, or legs; or
being unable to sit still.
Less serious Zyprexa Relprevv side effects may include:
tremors or shaking;
pain where the injection was given.
This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.
See also: Side effects (in more detail)
What other drugs will affect Zyprexa Relprevv?
Tell your doctor about all other medicines you use, especially:
blood pressure medication;
temazepam (Restoril); or
if you take olanzapine by mouth (Zyprexa, Symbyax, or Zyprexa Zydis).
This list is not complete and other drugs may interact with Zyprexa Relprevv. Tell your doctor about all medications you use. This includes prescription, over-the-counter, vitamin, and herbal products. Do not start a new medication without telling your doctor.
Compare with other treatments for:
Where can I get more information?
- Your doctor or pharmacist can provide more information about Zyprexa Relprevv.
- Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Zyprexa Relprevv only for the indication prescribed.
- Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
Copyright 1996-2014 Cerner Multum, Inc. Version: 1.01. Revision Date: 2011-10-16, 2:14:27 PM.