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Dermovate® Cream
Clobetasol Propionate 0.05% w/w Cream
(clobetasol propionate)
This medicine is available using any of the above names but will be
referred to as Dermovate throughout this following leaflet.
Read all of this leaflet carefully before you start using this medicine
because it contains important information for you.
 Keep this leaflet. You may need to read it again.
 If you have any further questions, ask your doctor or pharmacist.
 This medicine has been prescribed for you only. Do not pass it on to
others. It may harm them, even if their signs of illness are the same as
 If you get any of the side effects, talk to your doctor or pharmacist. This
includes any possible side effects not listed in this leaflet. See section 4.
What is in this leaflet:
1. What Dermovate is and what it is used for
2. What you need to know before you use Dermovate
3. How to use Dermovate
4. Possible side effects
5. How to store Dermovate
6. Contents of the pack and other information

Warnings and precautions
Talk to your doctor or pharmacist before using Dermovate if:
 you have previously had an allergic reaction with another steroid
 you are applying the cream under an airtight dressing, including a
child’s nappy. These dressings make it easier for the active ingredient
to pass through the skin. It is possible to accidentally end up using too
much cream.
 you have psoriasis, your doctor will want to see you more often.
 you are applying the cream on broken skin or within skin folds.
 using for a chronic leg ulcer as you may be at increased risk of local
allergic reaction or infection.
 you are applying to a large surface area or within the skin folds.
 you are applying near eyes or on eyelids, as cataracts or glaucoma may
result if the cream repeatedly enters the eye.
 you are applying to thin skin such as the face or on children as their
skin is thinner than adults and as a result may absorb larger amounts.
Use on children should be limited to 5 days and reviewed weekly. Use
on the face should be limited to 5 days.
 dressing or bandages should not be used on children or on the face
where the cream is applied.
If you are not sure if any of the above apply to you, talk to your doctor or
pharmacist before using this medicine.

Guidance on how to apply the cream
1 Wash your hands.
2 Apply a thin layer to the affected area(s) and gently rub into the skin
until it has all disappeared. You can measure how much Dermovate to
use with your fingertip. For children you will need to use less cream but
still use an adult finger to measure out the fingertip unit. This picture
shows one fingertip unit.

3 Unless you are meant to apply the cream to your hands as a part of the
treatment, wash them again after using the cream.
For an adult

Other medicines and Dermovate
Tell your doctor or pharmacist if you are taking, have recently taken or
might take any other medicine, especially if you are taking ritonavir and
itraconazole medications.

1. What Dermovate is and what it is used for
Dermovate contains a medicine called clobetasol propionate. It belongs to
a group of medicines called steroids. It helps to reduce swelling and

Pregnancy, breast-feeding and fertility
If you are pregnant or breast-feeding, think you may be pregnant or are
planning to have a baby, ask your doctor or pharmacist for advice before
taking this medicine.

Dermovate is used to help reduce the redness and itchiness of certain
skin problems. These skin problems include eczema, psoriasis, lichen
planus, discoid lupus, dermatitis and other skin conditions that have not
responded to milder steroid creams or ointments.

Dermovate Cream contains propylene glycol, cetostearyl alcohol
and chlorocresol
Propylene glycol may cause skin irritation. Cetostearyl alcohol may cause
local skin reactions (eg. contact dermatitis). Chlorocresol may cause
allergic reactions.

2. What you need to know before you use Dermovate
Do not use Dermovate:
 if you are allergic (hypersensitive) to clobetasol propionate or any of
the other ingredients of this medicine (listed in Section 6)
 on a child under 1 year old
 to treat any of the following skin problems, it could make them worse:
- acne
- severe flushing of skin on and around your nose (rosacea)
- spotty red rash around your mouth (perioral dermatitis)
- itching around your back passage or private parts
- infected skin (unless the infection is being treated with an antiinfective medicine at the same time)
- itchy skin which is not inflamed
Do not use if any of the above apply to you. If you are not sure, talk to
your doctor or pharmacist before using Dermovate.

3. How to use Dermovate
Always use this medicine exactly as your doctor has told you. Check with
your doctor or pharmacist if you are not sure.
Using this medicine
 You usually apply a thin layer of Dermovate 1 or 2 times a day. This
may be reduced as your skin begins to get better, or stopped when
 This cream is for use on your skin only.
 Do not use on large areas of the body for a long time (such as every
day for many weeks or months). If you need treatment for a long time,
your doctor may decide you need to use a milder cream or ointment
 The germs that cause infections like warm and moist conditions under
dressings so always clean the skin before a fresh dressing is put on.
 If you are applying the cream on someone else make sure you wash
your hands after use or wear disposable plastic gloves.
 If your skin problem does not improve in 2 to 4 weeks, talk to your

Do not worry if you find you need a little more or less than this. It is only a
rough guide.

Add/Amend 5 - This version replaces PIl dated 9.2.2015, previously
assessed against UK PIL dated August 2014.
A Chohan. 13 February 2015

For a child aged 1 – 10
Number of fingertip units needed


1-2 years




3-5 years





Child’s age

6-10 years


4. Possible side effects
Like all medicines, this medicine can cause side effects, although not
everybody gets them.




 Do not use it on children under 1 year of age.
 It is especially important in children not to exceed the prescribed
 A course of treatment for a child should not normally last more than 5
days - unless your doctor has told you to use it for longer. The doctor
may want to see the child every week, whilst using the cream.
If you have psoriasis
If you have thick patches of psoriasis on your elbows or knees, your
doctor may suggest applying the cream under an airtight dressing. It will
only be at night to help the cream to start working. After a short period of
time you will then apply the cream as normal.
If you apply Dermovate to your face
You should only apply the cream to your face if your doctor tells you to. It
should be limited to only 5 days as the skin on your face thins easily. Do
not let the cream get into your eyes. If it does, wash it out with plenty of
If you use more Dermovate than you should
If you apply too much or if accidentally swallowed, it could make you ill.
Talk to your doctor or go to hospital as soon as possible.
If you forget to use Dermovate
If you forget to apply your cream, apply it as soon as you remember. If it
is close to the time you are next meant to apply it, wait until this time.
If you stop using Dermovate
If you use Dermovate regularly make sure you talk to your doctor before
you stop using it as your condition may get worse if stopped suddenly.
If you have any further questions on the use of this medicine, ask your
doctor or pharmacist.

Stop using Dermovate and tell your doctor immediately if:
 you find that your skin problem gets worse, you develop a generalised
rash or your skin becomes swollen during treatment. You may be
allergic to the cream, have an infection or need other treatment.
 you have psoriasis and get raised bumps with pus under the skin. This
can happen during or after the treatment and is known as pustular
Other side effects you may notice when using Dermovate include:
Common (may affect up to 1 in 10 people)
 A feeling of burning, pain, irritation or itching where the cream is
Uncommon (may affect up to 1 in 100 people)
 Stretch marks may develop.
 Veins under the surface of your skin may become more noticeable.
Rare (may affect up to 1 in 1,000 people)
 An increased risk of infection
 An allergic skin reaction where the cream is applied
 Rash, itchy bumpy skin or redness of the skin
 Thinning and dryness of your skin and it may also damage or wrinkle
more easily
 An increase or reduction in hair growth or hair loss and changes in skin
 Weight gain, rounding of the face
 Delayed weight gain or slowing of growth in children
 Bones can become thin, weak and break easily
 Cloudy lens in the eye (cataract) or increased pressure in the eye
 Increased blood sugar levels or sugar in the urine
 High blood pressure
Reporting of side effects
If you get any side effects, talk to your doctor or pharmacist. This includes
any possible side effect not listed in this leaflet. You can also report side
effects directly via the Yellow Card Scheme at: By reporting side effects you can help
provide more information on the safety of this medicine.
5. How to store Dermovate
 Keep out of the sight and reach of children.
 Do not use Dermovate after the expiry date on the tube or carton (Exp).
The expiry date refers to the last day of that month.
 Do not store above 30°C. Store in the original package.
 Medicines should not be disposed of via wastewater or household
waste. Ask your pharmacist how to dispose of medicines no longer
required. These measures will help to protect the environment.
 If you notice any signs of discolouration or deterioration of this medicine
contact your pharmacist for advice.

6. Contents of the pack and other information
What Dermovate contains
 The active ingredient is clobetasol propionate.
Each 1 g cream contains 0.5 mg clobetasol propionate (0.05% w/w).
 Also contains glyceryl monostearate 40-55, cetostearyl alcohol,
beeswax substitute 6621, Arlacel 165, propylene glycol, chlorocresol,
sodium citrate, citric acid monohydrate and purified water.
What Dermovate looks like and contents of the pack
The Dermovate is available as white cream.
Available in pack of 25g aluminium tubes.
Manufacturer and Product Licence Holder
Manufactured by Glaxosmithkline Pharmaceuticals SA., ul. Grunwaldzka
189, Poznan PL-60-322, Poland.
Procured from within the EU by Product Licence holder:
Star Pharmaceuticals Ltd., 5 Sandridge Close, Harrow, Middlesex HA1
1XD. Repackaged by Servipharm Ltd.

PL No: 20636/2415

Leaflet revision and issue date Ref: 13.02.15[5]
Dermovate is a trademark of the Glaxo Group Ltd.
More Information
If you have any questions or are not sure about anything, ask your doctor
or pharmacist who will advise you. Other sources of information are:
National Eczema Society, Hill House, Highgate Hill, London N19 5NA
The Psoriasis Association, 2 Queensbridge, Northampton, NN4 7BF
You may also be able to find out more from books in public libraries.

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Source: Medicines and Healthcare Products Regulatory Agency

Disclaimer: Every effort has been made to ensure that the information provided here is accurate, up-to-date and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. This information has been compiled for use by healthcare practitioners and consumers in the United States. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective or appropriate for any given patient. If you have questions about the substances you are taking, check with your doctor, nurse or pharmacist.