Xigris Side Effects
Generic Name: drotrecogin alfa
Note: This document contains side effect information about drotrecogin alfa. Some of the dosage forms listed on this page may not apply to the brand name Xigris.
Some side effects of Xigris may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to drotrecogin alfa: intravenous powder for solution
Along with its needed effects, drotrecogin alfa (the active ingredient contained in Xigris) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor or nurse immediately if any of the following side effects occur while taking drotrecogin alfa:More common
For Healthcare Professionals
Applies to drotrecogin alfa: intravenous powder for injection
The most common side effect associated with drotrecogin alfa (the active ingredient contained in Xigris) has been bleeding.
Hematologic side effects have most commonly included bleeding (25% vs 18% with placebo). The majority of events were ecchymoses or gastrointestinal tract bleeding. Serious bleeding has been reported in 3.5% of patients (vs 2% with placebo) and included intracranial hemorrhage, life threatening hemorrhage, and any event requiring 3 or more units of packed red blood cells per days for 2 consecutive days.
Serious bleeding events have been reported at the following sites: Gastrointestinal, intra-abdominal, intrathoracic, retroperitoneal, intracranial, genitourinary, skin or soft tissues.
More about Xigris (drotrecogin alfa)
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