Succimer Side Effects

It is possible that some side effects of succimer may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.

For the Consumer

Applies to succimer: oral capsule

As well as its needed effects, succimer may cause unwanted side effects that require medical attention.

If any of the following side effects occur while taking succimer, check with your doctor or nurse as soon as possible:

Less common
  • Chills
  • fever

Some succimer side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

More common
  • Diarrhea
  • loose stools
  • loss of appetite
  • nausea and vomiting
  • skin rash

Succimer may cause your urine, sweat, and feces to have an unpleasant odor.

For Healthcare Professionals

Applies to succimer: oral capsule

Gastrointestinal

Gastrointestinal side effects (12% in children and 20.9% in adults) have included nausea, vomiting, diarrhea, appetite loss, hemorrhoidal symptoms, loose stools, and metallic taste in mouth. Abdominal cramps and stomach pain have also been reported in patients receiving succimer.[Ref]

General

General side effects (5.2% in children and 15.7% in adults) have included back pain, head pain, rib pain, chills, flank pain, fever, flu-like symptoms, heavy head/tired, head cold, headache, and moniliasis.[Ref]

Metabolic

Metabolic side effects (4.2% in children and 10.4% in adults) have included elevated serum cholesterol and increased proteinuria.[Ref]

Hepatic

Hepatic side effects (4.2% in children and 10.4% in adults) have included elevated SGPT, SGOT, and alkaline phosphatase.[Ref]

Respiratory

Respiratory side effects (3.7% in children and 0.7% in adults) have included rhinorrhea, nasal congestion, and cough.[Ref]

Genitourinary

Genitourinary side effects (3.7% in adults) have included decreased urination and voiding difficulty.[Ref]

Other

Other side effects (3.7% in children and 0.7% in adults) have included plugged ears, otitis media, and sore throat.[Ref]

Dermatologic

Dermatologic side effects (2.6% in children and 11.2% in adults) have included papular rash, herpetic rash, rash, mucocutaneous eruptions, and pruritus.[Ref]

Musculoskeletal

Musculoskeletal side effects (3.0% in adults) have included kneecap pain and leg pains.[Ref]

Cardiovascular

Cardiovascular side effects (1.8% in adults) have included arrhythmia.[Ref]

Nervous system

Nervous system side effects (1.0% in children and 12.7% in adults) have included drowsiness, dizziness, sensorimotor neuropathy, sleepiness, and paresthesia.[Ref]

Ocular

Ocular side effects (1.0% in children and 3.0% in adults) have included cloudy film in eye and watery eyes.[Ref]

Hematologic

Hematologic side effects (0.5% in children and 1.5% in adults) have included mild to moderate neutropenia, increased platelet count, and intermittent eosinophilia.[Ref]

References

1. "Product Information. Chemet (succimer)." McNeil Pharmaceutical, Raritan, NJ.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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