Prostin VR Pediatric Side Effects
Generic Name: alprostadil
Note: This page contains side effects data for the generic drug alprostadil. It is possible that some of the dosage forms included below may not apply to the brand name Prostin VR Pediatric.
It is possible that some side effects of Prostin VR Pediatric may not have been reported. These can be reported to the FDA here. Always consult a healthcare professional for medical advice.
For the Consumer
Applies to alprostadil: kit, powder for solution, solution, suppository
As well as its needed effects, alprostadil (the active ingredient contained in Prostin VR Pediatric) may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking alprostadil, check with your doctor immediately:Rare
- Curving of penis with pain during erection
- erection continuing for 4 to 6 hours
- erection continuing longer than 6 hours with severe and continuing pain of the penis
- swelling in or pain of the testes
Some alprostadil side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:More common
- Bleeding and pain at the injection site (short-term)
- painful erection
- Bruising or clotted blood in the penis at the injection site, usually caused by an incorrect injection
For Healthcare Professionals
Applies to alprostadil: compounding powder, injectable kit, injectable powder for injection, injectable solution, transurethral suppository
Local side effects have included penile pain (37%), prolonged erection (4%), penile fibrosis (3%), injection site hematoma (3%), penis disorder (3%), injection site ecchymosis (2%), penile rash (1%), penile edema (1%), balanitis, injection site hemorrhage, injection site inflammation, injection site itching, injection site swelling and edema, urethral bleeding, penile warmth, numbness, yeast infection, irritation, sensitivity, phimosis, pruritus, erythema, venous leak, painful erection, and abnormal ejaculation. Postmarketing experience has included reports of needle breakage.[Ref]
Hemodynamic changes manifested as hypotension and increases in pulse rate were generally observed at doses above 20 mcg and 30 mcg respectively, and appeared to be dose-dependent. These changes were usually reported as clinically unimportant, and only three patients discontinued treatment because of symptomatic hypotension.[Ref]
Cardiovascular side effects have included hypertension (2%), hypotension, vasodilation, peripheral vascular disorder, supraventricular extrasystoles, vasovagal reactions, and increases in pulse rate.[Ref]
Nervous system side effects have included headache (2%), dizziness (1%), hypesthesia, and non-generalized weakness.[Ref]
Musculoskeletal side effects have included back pain (1%) and leg cramps.[Ref]
Respiratory side effects have included upper respiratory infection (4%), flu syndrome (2%), sinusitis (2%), nasal congestion (1%), and cough (1%).[Ref]
Genitourinary side effects have included prostatic disorder (2%), testicular pain, scrotal disorder, scrotal edema, hematuria, testicular disorder, impaired urination, urinary frequency, urinary urgency, and pelvic pain.[Ref]
Ocular side effects have included mydriasis.[Ref]
Gastrointestinal side effects have rarely included nausea and dry mouth.[Ref]
Other side effects have included localized pain (2%), trauma (2%), diaphoresis, rash, non-application site pruritus, skin neoplasm, and increased serum creatinine.
Postmarketing reports: Device malfunction/failure[Ref]
1. "Product Information. Caverjet Sterile Powder (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI.
2. "Product Information. Muse (alprostadil)" Vivus Inc, Menlo Park, CA.
More about Prostin VR Pediatric (alprostadil)
- Prostin VR Pediatric injectable and transurethral
- Prostin VR Pediatric (Advanced Reading)
- Prostin VR Pediatric Intravenous (Advanced Reading)
Related treatment guides
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