Opicapone Side Effects
Applies to opicapone: oral capsule.
Serious side effects of Opicapone
Along with its needed effects, opicapone may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking opicapone:
More common
- Twitching, twisting, uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
Less common
- Blurred vision
- confusion
- dizziness, fainting, or lightheadedness when getting up suddenly from a lying or sitting position
- headache
- nervousness
- pounding in the ears
- seeing, hearing, or feeling things that are not there
- slow or fast heartbeat
- sweating
- unusual tiredness or weakness
Other side effects of Opicapone
Some side effects of opicapone may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:
More common
Less common
- Dry mouth
- trouble sleeping
- weight loss
For Healthcare Professionals
Applies to opicapone: oral capsule.
General
The most commonly reported adverse reaction was dyskinesia.[Ref]
Nervous system
Very common (10% or more): Dyskinesia (17.7%)
Common (1% to 10%): Dizziness, headache, somnolence
Uncommon (0.1% to 1%): Dysgeusia, hyperkinesia, syncope
Postmarketing reports: Balance disorder, hyperkinesia tremor[Ref]
Psychiatric
Common (1% to 10%): Abnormal dreams, hallucination, visual hallucination, insomnia
Uncommon (0.1% to 1%): Anxiety, depression, auditory hallucination, nightmares, sleep disorder
Postmarketing reports: Agitation, psychotic disorder, confusional state[Ref]
Cardiovascular
Common (1% to 10%): Orthostatic hypotension
Uncommon (0.1% to 1%): Palpitations, hypertension, hypotension[Ref]
Gastrointestinal
Common (1% to 10%): Constipation, dry mouth, vomiting
Uncommon (0.1% to 1%): Abdominal distention, abdominal pain, upper abdominal pain, dyspepsia
Postmarketing reports: Diarrhea, nausea[Ref]
Metabolic
Uncommon (0.1% to 1%): Decreased appetite, hypertriglyceridemia, decreased weight[Ref]
Respiratory
Uncommon (0.1% to 1%): Dyspnea[Ref]
Genitourinary
Uncommon (0.1% to 1%): Chromaturia, nocturia[Ref]
Musculoskeletal
Common (1% to 10%): Muscle spasms
Uncommon (0.1% to 1%): Muscle twitching, musculoskeletal stiffness, myalgia, extremity pain[Ref]
Ocular
Uncommon (0.1% to 1%): Dry eye
Other
Common (1% to 10%): Blood creatine phosphokinase increased
Uncommon (0.1% to 1%): Ear congestion
Postmarketing reports: Fatigue, malaise[Ref]
More about opicapone
- Check interactions
- Compare alternatives
- Reviews (1)
- Dosage information
- During pregnancy
- Drug class: dopaminergic antiparkinsonism agents
- En español
Patient resources
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Related treatment guides
References
1. Cerner Multum, Inc. UK Summary of Product Characteristics.
2. Product Information. Ongentys (opicapone). Neurocrine Biosciences, Inc. 2020.
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Some side effects may not be reported. You may report them to the FDA.
