MenHibrix Side Effects

Generic Name: haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine

Note: This document contains side effect information about haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine. Some of the dosage forms listed on this page may not apply to the brand name MenHibrix.

Some side effects of MenHibrix may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine: intramuscular powder for injection

Your child should not receive a booster vaccine if he or she had a life threatening allergic reaction after the first shot. Keep track of any and all side effects your child has after receiving this vaccine. When the child receives a booster dose, you will need to tell the doctor if the previous shot caused any side effects.

Becoming infected with haemophilus B influenza or meningitis is much more dangerous to your child's health than receiving this vaccine. However, like any medicine, this vaccine can cause side effects but the risk of serious side effects is extremely low.

Get emergency medical help if your child has any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if the child has a serious side effect such as:

  • severe weakness, trouble breathing;

  • extreme drowsiness, fainting;

  • fussiness, irritability, crying for an hour or longer;

  • seizure (convulsions); or

  • high fever (within a few hours or a few days after the vaccine).

Less serious side effects of haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine may include:

  • redness, pain, swelling, or a lump where the shot was given;

  • low fever;

  • mild fussiness or crying;

  • loss of appetite;

  • drowsiness; or

  • diarrhea.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine: intramuscular powder for injection


Dermatologic side effects have included postmarketing reports of rash and urticaria.


General side effects have included loss of appetite (up to 33.8%) and fever (up to 25.9%).


Immunologic side effects have included postmarketing reports of allergic reactions (including anaphylactic and anaphylactoid reactions) and angioedema.


Local side effects have included pain (up to 46.2%), redness (up to 35.5%), and swelling (up to 25.4%). Postmarketing reports have included extensive swelling of the vaccinated limb and injection site induration.

Nervous system

Nervous system side effects have included irritability (up to 70.8%) and drowsiness (up to 62.8%). Postmarketing reports have included convulsions (with or without fever), hypotonic-hyporesponsive episode, somnolence, and syncope or vasovagal responses to injection.


Respiratory side effects have included postmarketing reports of apnea.

More about MenHibrix (haemophilus b conjugate (prp-t) vaccine / meningococcal conjugate vaccine)

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