LoKara Side Effects
Generic Name: desonide topical
Note: This page contains information about the side effects of desonide topical. Some of the dosage forms included on this document may not apply to the brand name LoKara.
Not all side effects for LoKara may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to desonide topical: topical application cream, topical application foam, topical application gel/jelly, topical application lotion, topical application ointment
In addition to its needed effects, some unwanted effects may be caused by desonide topical (the active ingredient contained in LoKara). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking desonide topical:Less common
- Blistering, burning, crusting, dryness, or flaking of the skin
- burning, itching, redness, skin rash, swelling, or soreness at the application site
- flushing or redness of the skin
- itching, scaling, severe redness, soreness, or swelling of the skin
- peeling of the skin
- raised, dark red, wart-like spots on the skin, especially when used on the face
- stinging and burning
- unusually warm skin
- Redness and scaling around the mouth
- thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (e.g., between the fingers)
Some of the side effects that can occur with desonide topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Body aches or pain
- difficulty with breathing
- ear congestion
- loss of voice
- nasal congestion
- runny nose
- sore throat
- unusual tiredness or weakness
- Cold flu-like symptoms
- noisy breathing
- shortness of breath
- tender, swollen glands in the neck
- tightness in the chest
- trouble with swallowing
- voice changes
- Acne or pimples
- burning and itching of the skin with pinhead-sized red blisters
- burning, itching, and pain in hairy areas, or pus at the root of the hair
- lightening of normal skin color
- lightening of treated areas of dark skin
- reddish purple lines on the arms, face, legs, trunk, or groin
For Healthcare Professionals
Applies to desonide topical: compounding powder, topical cream, topical foam, topical gel, topical kit, topical lotion, topical ointment
The use of low potency topically applied corticosteroids has been generally well tolerated.[Ref]
Endocrinologic side effects of topical corticosteroids have been rare. Rarely, the hypothalamic-pituitary-adrenal axis has been suppressed. This suppression was more likely when higher potency topical steroids were used over extensive areas and when occlusive dressings were used.[Ref]
Skin on the face, axillae, and groin appear to be most susceptible to the adverse, long-term effects of topical steroids.
Topical corticosteroid use may inhibit local immune response rendering the skin more susceptible to infections. Folliculitis has occasionally been reported.
Perioral dermatitis or rosacea-like dermatitis has occurred in patients treated with potent topical corticosteroids who are of seborrheic skin type. This condition may flare temporarily upon discontinuation of topical steroids, prompting patients to continue their use. If topical corticosteroids are discontinued, this flare and the initial dermatitis generally resolves over a few weeks.[Ref]
Local side effects have commonly included burning, itching, or irritation, especially when applied to denuded skin or with occlusive dressings. Long-term use of topical corticosteroids has resulted in skin atrophy and thinning, and the development of striae, telangiectasia, subcutaneous hemorrhage, and easy bruising and bleeding. Allergic contact dermatitis has been occasionally reported.[Ref]
1. "Product Information. Tridesilon (desonide topical)." Bayer, West Haven, CT.
2. Cerner Multum, Inc. "Australian Product Information." O 0
3. "Product Information. Desowen (desonide topical)." Galderma Laboratories Inc, Fort Worth, TX.
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