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Side Effects > Kayexalate

Kayexalate Side Effects

Generic Name: Sodium Polystyrene Sulfonate

Please note - some side effects for Kayexalate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).


For the consumer

For the professional

Side Effects of Kayexalate - for the consumer


Kayexalate Powder

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Kayexalate Powder:

Appetite loss; constipation; nausea; upset stomach; vomiting.

Seek medical attention right away if any of these SEVERE side effects occur when using Kayexalate Powder:

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); change in emotions, mood, or behavior; change in heartbeat; muscle cramps; swelling of the feet or hands; unexplained muscle weakness.

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For the professional


Kayexalate

Kayexalate may cause some degree of gastric irritation. Anorexia, nausea, vomiting, and constipation may occur especially if high doses are given. Also, hypokalemia, hypocalcemia, and significant sodium retention, and their related clinical manifestations, may occur. Occasionally diarrhea develops. Large doses in elderly individuals may cause fecal impaction. Rare instances of colonic necrosis have been reported. Intestinal obstruction due to concretions of aluminum hydroxide, when used in combination with Kayexalate, has been reported.

The following events have been reported from worldwide post marketing experience:

  • Fecal impaction following rectal administration, particularly in children;
  • Gastrointestinal concretions (bezoars) following oral administration;
  • Gastrointestinal tract ulceration or necrosis which could lead to intestinal perforation; and,
  • Rare cases of acute bronchitis and/or broncho-pneumonia associated with inhalation of particles of polystyrene sulfonate.

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More resources:

Cerner Multum Kayexalate

MedFacts Kayexalate Powder

FDA Sodium Polystyrene Sulfonate

FDA Kionex

Facts & Comparisons Sodium Polystyrene Sulfonate

FDA Kayexalate

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