Ferrous fumarate Side Effects

Brand Names: Feostat, Ircon

Please note - some side effects for Ferrous fumarate may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Ferrous fumarate - for the Consumer

Ferrous Fumarate/Folic Acid

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Folic Acid:

Bitter taste; constipation; diarrhea; nausea; stomach discomfort; throat irritation.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black or green bowel movements; vomiting with continuing stomach pain.

Ferrous Fumarate/Docusate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Docusate:

Bitter taste; constipation; darkened or green stools; diarrhea; nausea; stomach upset; throat irritation.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate/Folic Acid/Sodium Docusate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Folic Acid/Sodium Docusate:

Constipation; darkened or green stools; diarrhea; indigestion; nausea; stomach cramps; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing stomach pain.

Ferrous Fumarate/Vitamin C

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Vitamin C:

Constipation; darkened or green stools; diarrhea; nausea; stomach upset.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate:

Constipation; diarrhea; green stools; nausea; stomach upset.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid:

Constipation; diarrhea; heartburn; loss of appetite; nausea; stomach upset; vomiting.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stools; fever; severe or persistent vomiting with continuing stomach pain.

Ferrous Fumarate/Folic Acid/B Complex/Vitamin C/Minerals

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Folic Acid/B Complex/Vitamin C/Minerals:

Constipation; darkened or green stools; diarrhea; loss of appetite; nausea; stomach discomfort.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; severe or persistent stomach pain.

Ferrous Fumarate/Polysaccharide Iron Complex/Vitamin C/Vitamin B3

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Polysaccharide Iron Complex/Vitamin C/Vitamin B3:

Constipation; diarrhea; loss of appetite; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; severe or persistent stomach pain.

Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid/Vitamin B Complex/Vitamin C/Biotin

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid/Vitamin B Complex/Vitamin C/Biotin:

Constipation; diarrhea; loss of appetite; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; numbness or tingling of the skin; severe or persistent stomach pain or cramping.

Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid/Vitamin C/Vitamin B3

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Polysaccharide Iron Complex/Folic Acid/Vitamin C/Vitamin B3:

Constipation; diarrhea; heartburn; loss of appetite; nausea; vomiting.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; severe or persistent stomach pain.

Ferrous Fumarate Chewable Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate Chewable Tablets:

Constipation; darkened or green stools; diarrhea; nausea; stomach upset.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate/Docusate Controlled-Release Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate/Docusate Controlled-Release Tablets:

Bitter taste; constipation; diarrhea; green stools; nausea; stomach upset; throat irritation.

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate Controlled-Release Tablets

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate Controlled-Release Tablets:

Constipation; diarrhea; green stools; nausea; stomach upset.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Ferrous Fumarate Suspension

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Ferrous Fumarate Suspension:

Constipation; darkened or green stools; diarrhea; nausea; stomach upset.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry stools; blood or streaks of blood in the stool; fever; vomiting with continuing sharp stomach pain.

Side Effects by Body System

Gastrointestinal

Gastrointestinal side effects are generally dose-related and have included nausea, constipation, anorexia, heartburn, vomiting and diarrhea. In addition, stools may appear darker in color in patients taking ferrous fumarate.

Oral preparations may rarely cause Hemoccult-positive stools, patients with positive tests generally require further work-up.

Gastrointestinal discomfort may be minimized by initiating ferrous fumarate therapy at smaller doses and gradually titrating upwards until the desired dose is achieved.

Gastrointestinal discomfort may also be minimized by administering each dose with food. However, concurrent administration of ferrous fumarate with food may decrease the amount of iron absorbed.

Constipation may be relieved by administering docusate sodium 100 mg to 200 mg per day in addition to increasing the intake of oral fluids, such as water.

Immunologic

It has been hypothesized that gastroenteritis is caused by bacteria that become virulent in the presence of iron overload resulting in a systemic infection. Treatment consists of discontinuing deferoxamine and initiating appropriate antimicrobial therapy.

Immunologic side effects have rarely included gastroenteritis associated with Yersinia enterocolitica and Listeria monocytogenes in patients with iron overload status receiving treatment with deferoxamine.

Local

Local side effects have included gangrene.

Localized corrosion has been reported in a pregnant woman taking ferrous sulfate (tablet) that lodged in a Meckel's diverticulum.

There have also been reports of wax-matrix ferrous sulfate tablets (delayed-release) lodging in the bowels of patients with strictures.

Other

Stained teeth have primarily occurred following ingestion of ferrous fumarate liquid preparation. Liquid dosage forms should be diluted in juice or water and sipped through a straw to aid in prevention of staining.

Iron overload (i.e., hemosiderosis) has been reported in patients genetically predisposed, or have underlying disorders, that augment the absorption of iron. It has also occurred following administration of excessive parenteral iron therapy, combination of oral and parenteral iron, or in patients with hemoglobinopathies that were erroneously diagnosed as iron deficiency anemia. Hemosiderosis is treated with repeated phlebotomy or long-term administration of deferoxamine. The liver is particularly susceptible to toxicity in iron-overload states.

Other side effects have included stained teeth and iron overload (hemosiderosis). Secondary hemochromatosis due to prolonged iron ingestion has been reported rarely.

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