Factor XIII Side Effects
Not all side effects for factor XIII may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to factor XIII: intravenous powder for solution
In addition to its needed effects, some unwanted effects may be caused by factor XIII. In the event that any of these side effects do occur, they may require medical attention.
If any of the following side effects occur while taking factor XIII, check with your doctor or nurse immediately:More common
- Bloody nose
- collection of blood under the skin
- deep, dark purple bruise
- itching, pain, redness, or swelling
- Chest pain
- dizziness or fainting
- pain in the chest, groin, or legs, especially the calves
- puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
- red, scaly, swollen, or peeling areas of the skin
- severe, sudden headache
- shortness of breath
- tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area
- unusual tiredness or weakness
Some of the side effects that can occur with factor XIII may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:More common
- Difficulty with moving
- general feeling of discomfort or illness
- joint pain
- muscle aches and pains
For Healthcare Professionals
Applies to factor XIII: intravenous powder for injection
Hypersensitivity side effects have included allergy, rash, pruritus, and erythema, chills/rise in temperature, arthralgia, headache, elevated thrombin antithrombin levels, and an increase in hepatic enzymes.
Hematologic side effects have included factor XIII inhibitor formation.
Cardiovascular side effects have included thrombosis and embolism.
General side effects have included flu-like syndrome and pyrexia.
Gastrointestinal side effects have included abdominal pain, diarrhea and vomiting.
Musculoskeletal side effects have included contusion, joint injury, limb injury, road traffic accident, and arthralgia.
Respiratory side effects have included upper respiratory tract infection and epistaxis.
Nervous system side effects have included headache and head injury.
Immunologic side effects have included allergic/anaphylactic reaction (including cutaneous reactions, alteration in blood pressure, nausea, dyspnea, fever, and chills).
More about factor XIII
- Coagulation factor XIII a-subunit (recombinant)
- Coagulation factor XIII concentrate (human)
- Factor XIII
- Coagulation factor xiii Intravenous (Advanced Reading)
- Factor xiii Intravenous (Advanced Reading)
- Factor xiii human Intravenous (Advanced Reading)
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