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Cytomegalovirus immune globulin Side Effects

Medically reviewed by Drugs.com. Last updated on Aug 22, 2023.

Applies to cytomegalovirus immune globulin: parenteral injection for iv infusion.

Side effects include:

Flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, wheezing/shortness of breath/chest tightness.

For Healthcare Professionals

Applies to cytomegalovirus immune globulin: intravenous solution.

General

The most common adverse events were flushing, chills, muscle cramps, back pain, fever, nausea, vomiting, arthralgia, and wheezing. Such reactions are most often related to infusion rates.[Ref]

Renal

Frequency not reported: Increases in serum creatinine, increase in blood urea nitrogen (BUN), acute renal failure, acute tubular necrosis, proximal tubular nephropathy, osmotic nephrosis[Ref]

Cardiovascular

Uncommon (0.1% to 1%): Decrease in blood pressure

Frequency not reported: Flushing

Postmarketing reports: Cardiac arrest, thromboembolism, vascular collapse, hypotension[Ref]

Dermatologic

Postmarketing reports: Stevens-Johnson syndrome, epidermolysis, erythema multiforme, bullous dermatitis[Ref]

Gastrointestinal

Frequency not reported: Nausea, vomiting

Postmarketing reports: Abdominal pain[Ref]

Hematologic

Postmarketing reports: Pancytopenia, leukopenia, hemolysis, positive direct antiglobulin (Coombs) test[Ref]

Hepatic

Postmarketing reports: Hepatic dysfunction[Ref]

Musculoskeletal

Frequency not reported: Chills, muscle cramps, back pain, arthralgia[Ref]

Nervous system

Postmarketing reports: Coma, loss of consciousness, seizures, tremor[Ref]

Respiratory

Frequency not reported: Wheezing

Postmarketing reports: Apnea, acute respiratory distress syndrome (ARDS), transfusion related acute lung injury (TRALI), cyanosis, hypoxemia, pulmonary edema, dyspnea, bronchospasm[Ref]

Other

Postmarketing reports: Fever, rigors[Ref]

Genitourinary

Frequency not reported: Oliguria, anuria requiring dialysis

References

1. Product Information. Cytogam (cytomegalovirus immune globulin). CSL Behring LLC. 2002.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.