Antagon Side Effects

Generic Name: ganirelix

Note: This document contains side effect information about ganirelix. Some of the dosage forms listed on this page may not apply to the brand name Antagon.

Some side effects of Antagon may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to ganirelix: subcutaneous solution

Along with its needed effects, ganirelix (the active ingredient contained in Antagon) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking ganirelix:

Less common
  • Abdominal or stomach pain
  • bloating
  • diarrhea
  • rapid weight gain
Rare
  • Cough
  • difficulty with swallowing
  • dizziness
  • fast heartbeat
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • shortness of breath
  • skin rash, hives, or itching
  • tightness in the chest
  • unusual tiredness or weakness

Some side effects of ganirelix may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Less common
  • Headache
  • redness, pain, or swelling at the injection site

For Healthcare Professionals

Applies to ganirelix: subcutaneous solution

Genitourinary

Genitourinary symptoms of abdominal pain (4.8%), ovarian hyperstimulation (2.4%), and vaginal bleeding (1.8%) have been reported.

Nervous system

Nervous systems side effects have been limited to headache in 3% of patients.

Local

Local side effects have included non-specific injection site reactions (1.1%).

Gastrointestinal

Gastrointestinal side effects of nausea and abdominal pain have occurred in 1.1% and 1% of patients, respectively.

Other

Follow-up studies of 282 newborns revealed 3 neonates with major and 18 with minor congenital anomalies. The major anomalies included hydrocephalus/meningocele, omphalocele, and Beckwith-Wiedemann Syndrome. Minor dermal, skeletal, muscular, and organ (angioma, hernia , testes, and renal) anomalies were reported.

Neonatal congenital anomalies have been reported. The causal relationship of the anomalies and ganirelix therapy is unknown. Multiple factors may confound assisted reproductive procedures.

Hypersensitivity

Hypersensitivity side effects have included postmarketing reports of hypersensitivity reactions, including anaphylactoid reactions with the first dose.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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