Skip to Content
Questions about Atrial Fibrillation? Get answers from our expert.

Vasopressin Pregnancy and Breastfeeding Warnings

Vasopressin is also known as: Pitressin, Vasostrict

Vasopressin Pregnancy Warnings

There have been several reports in which vasopressin or desmopressin (DDAVP) was used safely to treat diabetes insipidus during human pregnancy. There appears to be a decrease in the plasma concentration of vasopressin during the first and second trimesters, and a 3-fold increase in the plasma concentration of vasopressin in the last trimester and during labor. In vivo and in vitro data have shown that vasopressin and other structurally related polypeptides increase the frequency and amplitude of uterine contractions.

Vasopressin has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Vasopressin is only recommended for use during pregnancy when benefit outweighs risk.

Vasopressin Breastfeeding Warnings

There are no data on the excretion of vasopressin into human milk. Patients receiving vasopressin or other structurally related polypeptides have been reported to breast-feed without apparent adverse effects on the nursing infant. The manufacturer recommends that caution be used when administering vasopressin to nursing women.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.