Triprolidine Pregnancy and Breastfeeding Warnings

Brand names: Histex, Histex PD Drops, Histex Syrup, M-Hist PD, Tripohist, Vanaclear PD, Vanahist PD, Zymine, Zymine XR

Medically reviewed by Drugs.com. Last updated on Aug 2, 2023.

Triprolidine Pregnancy Warnings

Animal studies have not been reported. There are no controlled data in human pregnancy.

The manufacturer makes no recommendation regarding use during pregnancy.

US FDA pregnancy category: Not formally assigned to a pregnancy category.

Comments:
-Premature infants exposed to this drug near birth may be at higher risk of retrolental fibroplasia.
-Some experts recommend that patients who are pregnant should ask their healthcare provider prior to starting treatment.

See references

Triprolidine Breastfeeding Warnings

The manufacturer makes no recommendation regarding use during lactation.

Excreted into human milk: Yes

Comments:
-The American Academy of Pediatrics classifies this drug as compatible with breastfeeding.
-Some experts recommend the use of non-sedating antihistamines during lactation (e.g., desloratadine, fexofenadine, loratadine).

Use in larger doses and/or prolonged use, especially with sympathomimetics or before lactation, may result in a decreased milk supply and/or adverse effects in the breastfed infant. Antihistamines administered in relatively IV high doses to postpartum and nonlactating women have decreased basal serum prolactin; however, suckling-induced prolactin secretion was not affected by antihistamine pretreatment in postpartum patients.

See references

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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