Topotecan Pregnancy and Breast Feeding Warnings

Topotecan is also known as: Hycamtin

Overview

Do not use Topotecan if you are pregnant. It may cause harm to the fetus. Avoid becoming pregnant while you are taking it. If you think you may be pregnant, contact your doctor right away. It is not known if Topotecan is found in breast milk. Do not breast-feed while taking Topotecan .

Topotecan Pregnancy Warnings

Topotecan has been assigned to pregnancy category D by the FDA. Animal data have revealed evidence of maternal toxicity, embryolethality, reduced fetal body weight, fetal resorption, microphthalmia, and pre-implant loss. Topotecan may cause fetal harm when administered to a pregnant woman. There are no controlled data in human pregnancy. Women who are receiving topotecan should be advised to avoid pregnancy. If topotecan is used during pregnancy, or if the patient becomes pregnant while receiving the drug, she should be advised of the potential hazard to the fetus.

Topotecan Lactation Warnings

There are no data on the excretion of topotecan into human milk. The manufacturer states that topotecan should be discontinued when women are receiving topotecan.

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