Psyllium / senna Pregnancy and Breastfeeding Warnings
Psyllium / senna is also known as: Perdiem, SennaPrompt
Psyllium / senna Pregnancy Warnings
Senna has not been formally assigned to a pregnancy category by the FDA. Psyllium has not been formally assigned to a pregnancy category by the FDA. One study of sennosides A and B on rats and rabbits during organogenesis reported no evidence of teratogenicity. Animal studies on psyllium have not been reported. There are no controlled data in human pregnancy. The combination of psyllium and senna should only be given during pregnancy when benefit outweighs risk.
Psyllium / senna Breastfeeding Warnings
There are no data on the excretion of psyllium into human milk. Senna is not excreted into human milk. However, senna is a prodrug which is metabolized in vivo to the active sennosides (glucosides of rhein). Rhein is excreted into human milk in very small amounts. No adverse effects have been observed in nursing infants. The American Academy of Pediatrics considers senna to be compatible with breast-feeding.
References for pregnancy information
- "Product Information. Metamucil (psyllium)." Procter and Gamble Pharmaceutic, Cincinnati, OH.
References for breastfeeding information
- Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
- "Product Information. Perdiem Overnight Relief (psyllium)" Novartis Pharmaceuticals, East Hanover, NJ.
- Shepard TH. "Catalog of Teratogenic Agents 6th" Baltimore, MD: Johns Hopkins University Press (1989): 574-5