Nalidixic acid Pregnancy and Breast Feeding Warnings
Nalidixic acid is also known as: NegGram
Overview
If you become pregnant, contact your doctor. You will need to discuss the benefits and risks of using Nalidixic Acid Suspension while you are pregnant. It is not known if Nalidixic Acid Suspension is found in breast milk. Do not breast-feed while taking Nalidixic Acid Suspension.
Nalidixic acid Pregnancy Warnings
Nalidixic acid has been assigned to pregnancy category C by the FDA. Animal studies have revealed teratogenic and embryocidal effects and prolonged pregnancy duration. There are no controlled data in human pregnancy. No birth defects were reported in 63 newborns whose mothers had taken the drug during pregnancy. Cartilage damage and arthropathy are reported in immature animals giving rise to concern over effects on bone formation in the developing fetus. Because safer alternatives are available, some experts consider quinolones contraindicated during pregnancy, especially during the first trimester. Nalidixic acid is only recommended for use during pregnancy when benefit outweighs risk.
Nalidixic acid Lactation Warnings
Nalidixic acid is excreted into human milk in small amounts (0.003% of the maternal dose). Hemolytic anemia has been reported in an infant with G6PD deficiency. The manufacturer considers nalidixic acid to be contraindicated during lactation.
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