Nalidixic acid Pregnancy and Breastfeeding Warnings
Nalidixic acid is also known as: NegGram
Nalidixic acid Pregnancy Warnings
Nalidixic acid has been assigned to pregnancy category C by the FDA. Animal studies have revealed teratogenic and embryocidal effects and prolonged pregnancy duration. There are no controlled data in human pregnancy. No birth defects were reported in 63 newborns whose mothers had taken the drug during pregnancy. Cartilage damage and arthropathy are reported in immature animals giving rise to concern over effects on bone formation in the developing fetus. Because safer alternatives are available, some experts consider quinolones contraindicated during pregnancy, especially during the first trimester. Nalidixic acid is only recommended for use during pregnancy when benefit outweighs risk.
Nalidixic acid Breastfeeding Warnings
Nalidixic acid is excreted into human milk in small amounts (0.003% of the maternal dose). Hemolytic anemia has been reported in an infant with G6PD deficiency. The manufacturer considers nalidixic acid to be contraindicated during lactation.
- Nalidixic Acid use while Breastfeeding (in more detail)
- nalidixic acid Consumer Information
- Pregnancy Support Group
- FDA Pregnancy Categories
- Medicine use during Pregnancy
- Medicine use while Breastfeeding
- Safe Medications during Breastfeeding
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