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Metaproterenol Pregnancy and Breastfeeding Warnings

Metaproterenol is also known as: Alupent, Metaprel

Metaproterenol Pregnancy Warnings

Metaproterenol has been assigned to pregnancy category C by the FDA. Reproductive studies in mice and rabbits have demonstrated teratogenic and embryotoxic effects at doses at least 30 times the normal human oral dose. There are no controlled data in human pregnancy, although it has been used systemically to inhibit preterm labor. No fetal abnormalities have been reported with such use, however, the fetus may experience the general adverse effects reported in the mother. Use of metaproterenol in pregnant women for the relief of bronchospasm may interfere with uterine contractility. Metaproterenol is only recommended for use during pregnancy when benefit outweighs risk.

Metaproterenol Breastfeeding Warnings

There are no data on the excretion of metaproterenol into human milk. The manufacturer recommends that caution be used when administering metaproterenol to nursing women.

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