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Meropenem Pregnancy and Breastfeeding Warnings

Meropenem is also known as: Merrem, Merrem Novaplus

Meropenem Pregnancy Warnings

FDA pregnancy category: B Meropenem should be used during pregnancy only if clearly needed.

Animal studies have failed to reveal evidence of fetal harm, although slight changes in fetal body weight were noted. There are no controlled data in human pregnancy. FDA pregnancy category B: Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women.

Meropenem Breastfeeding Warnings

A mother was treated with meropenem 1 g IV every 8 hours for 7 days while her newborn was exclusively breastfed. Five samples of hindmilk were collected and the average breast milk level was 480 mcg/L. Estimated average and maximum infant intake were 71 mcg/kg/day (0.13% of weight-adjusted maternal dose) and 97 mcg/kg/day (0.18% of weight-adjusted maternal dose), respectively. When asked later, the mother stated her infant had no symptoms of oral thrush, watery diarrhea, or diaper dermatitis that needed antifungal therapy during therapy or during the month after finishing meropenem.

Caution is recommended. Excreted into human milk: Yes Excreted into animal milk: Data not available Meropenem has been used without apparent harmful effects in the nursing infant; clinical monitoring of infants for altered gastrointestinal flora suggested.

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