Measles virus vaccine/mumps virus vaccine/rubella virus vaccine Pregnancy and Breast Feeding Warnings
Measles virus vaccine/mumps virus vaccine/rubella virus vaccine is also known as: M-M-R II, M-M-R-II
Overview
Do not use Measles, Mumps, and Rubella Vaccine if you are pregnant. If you suspect that you could be pregnant, contact your doctor immediately. After receiving Measles, Mumps, and Rubella Vaccine , do not become pregnant for at least 3 months without checking with your doctor. It is unknown if Measles, Mumps, and Rubella Vaccine is excreted in breast milk. If you are or will be breast-feeding while you are using Measles, Mumps, and Rubella Vaccine , check with your doctor or pharmacist to discuss the risks to your baby.
Measles virus vaccine/mumps virus vaccine/rubella virus vaccine Pregnancy Warnings
Measles/mumps/rubella vaccine has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. There is a theoretical risk of viral transmission to the fetus. The manufacturer's labeling states that measles/mumps/rubella vaccination is considered contraindicated during pregnancy and that pregnancy should be avoided for 3 months following vaccination. The Advisory Committee on Immunization Practices recommends that pregnancy be avoided for 4 weeks after vaccination, that women who become pregnant within that period be advised of the theoretical risk to the fetus, and that vaccination during pregnancy is generally not a reason to terminate the pregnancy.
Abnormalities suggestive of congenital rubella syndrome were not observed during a 10-year survey of 700 pregnant women who received rubella vaccine within 3 months before or after conception. Mumps virus infection during the first trimester may increase the rate of spontaneous abortion. Although mumps vaccine virus has been shown to infect the placenta and fetus, there is no evidence of congenital malformations in humans. Natural measles virus infection during pregnancy has been associated with an increased incidence of spontaneous abortion, stillbirth, congenital defects, and prematurity. There are no data on the use of measles virus vaccine during pregnancy; however, it is possible that the vaccine virus may also induce adverse fetal effects.
Measles virus vaccine/mumps virus vaccine/rubella virus vaccine Lactation Warnings
Rubella vaccine virus may be excreted in breast milk and transmitted to nursing infants. Severe disease has not been reported in exposed infants who were serologically positive for rubella infection; however, one infant had a mild illness characteristic of acquired rubella. There are no data on the excretion of measles or mumps vaccine virus into human milk. The manufacturer recommends that caution be used when administering measles/mumps/rubella vaccine to breast-feeding women. The U.S. Centers for Disease Control and Prevention (CDC) consider the administration of live virus vaccines compatible with breast-feeding.
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This drug information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information in contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
