Skip to Content

Measles virus vaccine / mumps virus vaccine / rubella virus vaccine Pregnancy and Breastfeeding Warnings

Measles virus vaccine / mumps virus vaccine / rubella virus vaccine is also known as: M-M-R II

Measles virus vaccine / mumps virus vaccine / rubella virus vaccine Pregnancy Warnings

Animal studies have not been conducted. There are no controlled data in human pregnancy. A 10 year survey of over 700 women who received rubella vaccination within 3 months of conception (before or after) did not show any abnormalities compatible with congenital rubella syndrome. Mumps infection in the first trimester may increase the rate of spontaneous abortion. Mumps vaccine virus can infect the placenta and fetus, but there is no evidence of it causing congenital malformations. Wild type measles during pregnancy increases the risk of spontaneous abortion, stillbirth, congenital defects, and prematurity; it is prudent to assume the vaccine virus strain can induce fetal effects. Inadvertent vaccination should not be a reason for terminating a pregnancy. AU TGA pregnancy category B2: Drugs which have been taken by only a limited number of pregnant women and women of childbearing age, without an increase in the frequency of malformation or other direct or indirect harmful effects on the human fetus having been observed. Studies in animals are inadequate or may be lacking, but available data show no evidence of an increased occurrence of fetal damage. US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

Use is contraindicated. AU TGA pregnancy category: B2 US FDA pregnancy category: C Comments: -Pregnancy should be avoided for 3 months after vaccination

See references

Measles virus vaccine / mumps virus vaccine / rubella virus vaccine Breastfeeding Warnings

Benefit should outweigh risk. Excreted into human milk: Unknown Excreted into animal milk: Data not available Comments: -Live attenuated rubella vaccine may secrete the virus in breast milk and transmit it to the infant.

See references

References for pregnancy information

  1. "Product Information. M-M-R II (measles/mumps/rubella virus vaccine)." Merck & Company Inc, West Point, PA.
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

References for breastfeeding information

  1. Cerner Multum, Inc. "Australian Product Information." O 0
  2. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0
  3. "Product Information. M-M-R II (measles/mumps/rubella virus vaccine)." Merck & Company Inc, West Point, PA.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide