Lovastatin / niacin Pregnancy and Breastfeeding Warnings

Lovastatin / niacin is also known as: Advicor

Lovastatin / niacin Pregnancy Warnings

Lovastatin-niacin has been assigned to pregnancy category X by the FDA. Animal studies for the combination product have not been reported, however lovastatin has been shown to produce skeletal malformations at plasma levels 40 times the human exposure (mice) and 80 times the human exposure (rats). There are no controlled data in human pregnancy. Lovastatin-niacin use is considered contraindicated during pregnancy.

Lovastatin / niacin Breastfeeding Warnings

There are no data on the excretion of lovastatin into human milk. Niacin is excreted in human milk. The effects in the nursing infant are unknown, however, the potential for serious adverse reactions in nursing infants from lipid-altering doses of lovastatin and niacin warrants that the drug(s) not be administered to nursing mothers. Lovastatin-niacin is considered contraindicated during breast-feeding by the American Academy of Pediatrics.

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.

Hide
(web5)