Erlotinib Pregnancy and Breast Feeding Warnings

Erlotinib is also known as: Tarceva

Overview

Do not use Erlotinib if you are pregnant. If you think you may be pregnant, contact your doctor right away. If you are able to become pregnant, use effective birth control while you are taking Erlotinib and for at least 2 weeks after treatment is complete. Talk with your doctor or pharmacist about effective methods of birth control. It is not known if Erlotinib is found in breast milk. Do not breast-feed while taking Erlotinib .

Erlotinib Pregnancy Warnings

Erlotinib has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of maternal toxicity with associated embryo/fetal lethality and abortion. In animal studies where the drug was given prior to mating through the first week of pregnancy, an increase in early resorptions which resulted in a decrease in the number of live fetuses has been reported. There are no controlled data in human pregnancy. Erlotinib should only be given during pregnancy when there are no alternatives and benefit outweighs risk.

Erlotinib Lactation Warnings

There are no data on the excretion of erlotinib into human milk. Because many drugs are excreted in human milk and because the effects of erlotinib on infants have not been studied, women should not breast-feed while receiving erlotinib therapy.

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