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Carmustine Pregnancy and Breastfeeding Warnings

Carmustine is also known as: BiCNU, Gliadel

Carmustine Pregnancy Warnings

Animal studies have reported that carmustine affects fertility in males at doses somewhat higher than the human dose.

Carmustine has been assigned to pregnancy category D by the FDA. Animal studies have revealed evidence of embryotoxicity and teratogenicity. There are no controlled data in human pregnancy. Carmustine should only be given during pregnancy when there are no alternatives and benefit outweighs risk. The manufacturer recommends that women of childbearing potential should be advised to avoid becoming pregnant.

Carmustine Breastfeeding Warnings

There are no data on the excretion of carmustine into human milk. The manufacturer recommends that because of the potential for serious adverse events in nursing infants, nursing should be discontinued while taking carmustine.

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