Skip to Content

Budesonide nasal Pregnancy and Breastfeeding Warnings

Budesonide nasal is also known as: Rhinocort, Rhinocort Allergy, Rhinocort Aqua

Budesonide nasal Pregnancy Warnings

Budesonide has been assigned to pregnancy category B by the FDA. At high doses given subcutaneously, budesonide has been shown to be teratogenic in rabbits and rats. Budesonide has not been shown to be teratogenic in animals when given in high doses by inhalation. The impact of budesonide on human pregnancy has been evaluated through assessments of birth registries linked with maternal usage of intranasally administered budesonide. The results from population-based prospective cohort epidemiological studies reviewing data from three Swedish registries from 1995-2001 indicate no increased risk for overall congenital malformations from the use of intranasal budesonide during early pregnancy. Budesonide is only recommended for use during pregnancy when benefit outweighs risk.

See references

Budesonide nasal Breastfeeding Warnings

There are no data on the excretion of budesonide into human milk. Other glucocorticoids are excreted into human milk in low concentrations. The manufacturer recommends that caution be used when administering budesonide nasal to nursing women.

Budesonide, like other corticosteroids, is secreted in human milk. Data with budesonide delivered orally via dry powder inhaler to women with asthma indicates that the total daily oral dose of budesonide in breast milk to the infant is approximately 0.3% to 1% of the dose inhaled by the mother. No studies have been conducted in breastfeeding women specifically with budesonide nasal; however, the dose of budesonide available to the infant in breast milk, as a percentage of the maternal dose, would be expected to be similar. Budesonide nasal should be used in nursing women only if clinically appropriate. Prescribers should weigh the known benefits of breastfeeding for the mother and infant against the potential risks of minimal budesonide exposure in the infant. Dosing considerations include prescription or titration to the lowest clinically effective dose and use of budesonide nasal immediately after breastfeeding to maximize the time interval between dosing and breastfeeding to minimize infant exposure. However, in general, budesonide nasal use should not delay or interfere with infant feeding.

See references

References for pregnancy information

  1. Mcdonald CF, Burdon JGW "Asthma in pregnancy and lactation - a position paper for the thoracic society of australia and new zealand." Med J Aust 165 (1996): 485-8
  2. "Product Information. Rhinocort (budesonide)." Astra USA, Westborough, MA.

References for breastfeeding information

  1. "Product Information. Rhinocort (budesonide)." Astra USA, Westborough, MA.
  2. Mcdonald CF, Burdon JGW "Asthma in pregnancy and lactation - a position paper for the thoracic society of australia and new zealand." Med J Aust 165 (1996): 485-8

See Also...

Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.