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Antivenin (crotalidae) polyvalent Pregnancy and Breastfeeding Warnings

Antivenin (crotalidae) polyvalent is also known as: Antivenin Polyvalent, CroFab

Antivenin (crotalidae) polyvalent Pregnancy Warnings

Crotalidae polyvalent immune Fab contains mercury in the form of ethyl mercury from thimerosal. Although there are limited toxicology data on ethyl mercury, high dose and acute exposures to methyl mercury have been associated with neurological and renal toxicities. Developing fetuses and very young children are most susceptible and therefore, at greater risk.

Crotalidae polyvalent immune Fab has been assigned to pregnancy category C by the FDA. Animal studies have not been reported. There are no controlled data in human pregnancy. Crotalidae polyvalent immune Fab should be used during pregnancy only if clearly needed. Polyvalent Crotalidae antivenin has not been formally assigned to a pregnancy category by the FDA. Pregnancy should not be considered a contraindication if the antivenin is clearly needed.

Antivenin (crotalidae) polyvalent Breastfeeding Warnings

There are no data on the excretion of polyvalent Crotalidae antivenin into human milk. No reports of adverse effects have been found in the medical literature.

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