Natural Products
Facts & Comparisons > Shark Liver Oil

Shark Liver Oil

Scientific names: Shark liver oil may be obtained from several species of sharks, including the deep sea shark (Centrophorus squamosus), the dogfish shark (Squalus acanthias), and the basking shark (Cetorhinus maximus).

Efficacy-safety rating:

●●...Ethno or other evidence of efficacy.

Safety rating:

...Little exposure or very minor concerns.

What is Shark Liver Oil?

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Shark liver oil (SLO) is commercially produced from several species of deep sea sharks' liver oil. The liver constitutes about 25% of the total shark body weight. SLO is a major natural source of squalene and alkyglycerols.

What is Shark Liver Oil used for?

Traditional/Ethnobotanical uses

SLO has been used for more than 40 years for its therapeutic benefits. Initially, it was employed by Scandinavian fishermen to treat skin conditions and certain cancers.

Miscellaneous uses

SLO has been used to prevent radiation sickness, to treat skin conditions, and as a cancer treatment. Alkylglycerols have been studied as an immune system stimulant. However, a conflicting report finds no documentation regarding inhibition of tumor growth in alkoxyglycerol-treated cancer patients, even though it is used in Denmark as a supplementary agent in cancer treatment. SLO demonstrates inhibitory actions on certain human cancers, but evidence is limited. SLO also has been classified as a topical protectant.

What is the dosage of Shark Liver Oil?

Shark liver oil marketed under the name isolutrol has been studied in a clinical trial of acne at a topical concentration of 0.15 g per 100 mL.

Is Shark Liver Oil safe?

Contraindications

Contraindications have not yet been identified.

Pregnancy/nursing

Information regarding safety and efficacy in pregnancy and lactation is lacking.

Interactions

None well documented.

Side Effects

Few toxic effects have been reported; advise caution with SLO concerning SLO-induced pneumonia.

Toxicities

In Sweden, a SLO product (Ecomer) was prohibited by the National Board of Health and Welfare.

References

  1. Shark Liver Oil. Review of Natural Products. factsandcomparisons4.0 [online]. 2004. Available from Wolters Kluwer Health, Inc. Accessed April 23, 2007.

Copyright © 2006 Wolters Kluwer Health




 

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