Daridorexant

Generic name: daridorexant [ DAR-i-doe-REX-ant ]
Brand name: Quviviq
Dosage form: oral tablet (25 mg; 50 mg)
Drug class: Miscellaneous anxiolytics, sedatives and hypnotics

Medically reviewed by Drugs.com on Oct 7, 2022. Written by Cerner Multum.

What is daridorexant?

Daridorexant is used in adults who have trouble staying or falling asleep (insomnia).

Daridorexant may also be used for purposes not listed in this medication guide.

Daridorexant side effects

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Tell your doctor right away if you have new or sudden changes in mood or behavior, including new or worse depression or have thoughts about suicide or hurting yourself.

Some people using daridorexant have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. Tell your doctor if this happens to you.

Call your doctor at once if you have an inability to move or talk for several minutes or if you have hallucinations while you are waking up or going to sleep.

Common side effects of daridorexant may include:

• headache; and

• drowsiness.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

Some people have thoughts about suicide while taking daridorexant. Tell your doctor right away if you have any sudden changes in mood or behavior, or thoughts about suicide.

Some people using daridorexant have engaged in activity such as driving, eating, walking, making phone calls, or having sex and later having no memory of the activity. Tell your doctor if this happens to you.

Before taking this medicine

You should not use daridorexant if you fall asleep often (narcolepsy).

Tell your doctor if you have ever had:

• mental illness, depression, or suicidal thoughts;

• drug or alcohol abuse or addiction;

• a condition called cataplexy (sudden onset of muscle weakness);

• daytime sleepiness;

• breathing problems, including sleep apnea (breathing that stops during sleep); or

• liver problems.

It is not known if daridorexant will harm an unborn baby. Tell your doctor if you are pregnant or plan to become pregnant.

If you are pregnant, your name may be listed on a pregnancy registry to track the effects of daridorexant on the baby.

Ask a doctor if it is safe to breastfeed while using daridorexant.

How should I take daridorexant?

Follow all directions on your prescription label and read all medication guides or instruction sheets. Use the medicine exactly as directed. Tell your doctor if you feel an increased urge to use more of this medicine.

Daridorexant may be habit-forming. Misuse can cause addiction, overdose, or death. Keep the medication where others cannot get to it. Selling or giving away this medicine is against the law.

Take daridorexant 30 minutes before going to bed only once every night.

Only take daridorexant if you can stay at least 7 hours in bed before being active again.

If daridorexant is taken with or right after a meal, this medicine may take longer to work.

Call your doctor if your sleep problem worsens or does not improve within 7 to 10 days.

Keep your medicine in a place where no one can use it improperly.

Store at room temperature away from moisture and heat.

Daridorexant dosing information

Usual Adult Dose for Insomnia:

Recommended dose: 25 to 50 mg once per night, orally
Maximum dose: 50 mg

Comments:
-Take no more than once per night within 30 minutes of going to bed, and with at least 7 hours remaining prior to awakening.
-The failure of insomnia to remit after 7 to 10 days of treatment may indicate the presence of a primary psychiatric or medical illness that should be evaluated.

Use: Treatment of adults with insomnia

What happens if I miss a dose?

Take the medicine as soon as you can if you take daridorexant on a regular basis. Do not take more than one dose in the same day. Skip the missed dose and go back to your normal dosing schedule if you will not be able to stay in bed for at least 7 hours after taking the missed dose.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while taking daridorexant?

Do not drink alcohol. Dangerous side effects or death could occur.

Avoid driving or hazardous activity until you know how daridorexant will affect you. Your reactions could be impaired.

What other drugs will affect daridorexant?

Sometimes it is not safe to use certain medicines at the same time. Some drugs can affect your blood levels of other drugs you use, which may increase side effects or make the medicines less effective.

Using daridorexant with other drugs that make you drowsy can worsen this effect. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may affect daridorexant, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all other medicines you use.

Popular FAQ

Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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