Is Vraylar (cariprazine) a controlled substance?
Vraylar (cariprazine) is not a controlled drug or substance.
Vraylar is an atypical antipsychotic used in the treatment of schizophrenia, in the acute treatment of manic or mixed episodes associated with bipolar I disorder, in the treatment of depressive episodes associated with bipolar I disorder, and as an add-on to antidepressants in the treatment of major depressive disorder.
Why might people think that Vraylar is a controlled drug?
Vraylar use may decrease substance abuse in patients with bipolar I disorder. Substance use disorders are sometimes treated with controlled drugs, such as methadone, and are commonly associated with bipolar I disorder and schizophrenia.
Certain drugs are classed as controlled substances
Some drugs, substances or chemicals are classified as controlled substances. These agents are more closely regulated and fall into one of five categories or schedules. Drugs with a high potential for abuse and potential to create severe dependence are listed as Schedule I drugs and those with the least potential for abuse are listed as Schedule V drugs.
References
- Food and Drug Administration (FDA). Vraylar. Highlights of Prescribing Information. [Accessed December 22, 2022]. Available online at: https://www.accessdata.fda.gov/drugsatfda_docs/label/2022/204370s009lbl.pdf
- Sanders LO, Miller JJ. Cariprazine May Decrease Substance Abuse in Patients with Bipolar I Disorders. Psychiatric Times. March 15, 2019. Vol 36, Issue 3. Available online at: https://www.psychiatrictimes.com/view/cariprazine-may-decrease-substance-abuse-patients-bipolar-i-disorder.
- Thoma P, Daum I. Comorbid substance use disorder in schizophrenia: A selective overview of neurobiological and cognitive underpinnings. Psychiatry and Clinical Neurosciences 2013; 67: 367–383. doi:10.1111/pcn.12072.
- United States Drug Enforcement Administration (DEA). Drug Scheduling. Controlled Substances. May 5. 2020. [Accessed February 2, 2021]. Available online at: https://www.deadiversion.usdoj.gov/schedules/orangebook/c_cs_alpha.pdf
- United States Drug Enforcement Administration (DEA). Drug Scheduling. [Accessed July 21, 2020]. Available online at: https://www.dea.gov/drug-scheduling.
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