Tlando Dosage

2.1 Important Dosage Information

TLANDO is not substitutable with other oral testosterone undecanoate products.

Confirmation of Hypogonadism Before Initiation of TLANDO

Prior to initiating TLANDO, confirm the diagnosis of hypogonadism by ensuring that serum testosterone concentrations have been measured in the morning on at least two separate days and that these serum testosterone concentrations are below the normal range.

2.3 Recommended Dosage

The recommended dosage of TLANDO is 225 mg (taken as two 112.5 mg capsules), orally twice daily, once in the morning and once in the evening. Take with food.

Monitoring for Continued Use or Discontinuation

Monitor serum testosterone (8 to 9 hours after the morning dose) 3 to 4 weeks after initiating TLANDO, and periodically thereafter. Based on serum testosterone measurements, determine if TLANDO should be continued or discontinued:

• Serum testosterone 300 - 1080 ng/dL: continue TLANDO
• Serum testosterone < 300 ng/dL: discontinue TLANDO
• Serum testosterone > 1080 ng/dL: discontinue TLANDO