Oleptro Dosage
Generic name: trazodone hydrochloride
Dosage form: tablet, extended release
This dosage information does not include all the information needed to use Oleptro safely and effectively. See full prescribing information for Oleptro.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Dose Selection
The recommended starting dose of Oleptro is 150 mg once daily in adults. The dose may be increased by 75 mg/day every three days (i.e., start 225 mg on Day 4 of therapy). The maximum daily dose should not exceed 375 mg.
- Oleptro tablets should be taken orally at the same time every day, in the late evening preferably at bedtime, on an empty stomach.
- Once an adequate response has been achieved, dosage may be gradually reduced, with subsequent adjustment depending on therapeutic response.
- Patients should be monitored for withdrawal symptoms when discontinuing treatment with trazodone hydrochloride. The dose should be gradually reduced whenever possible [see Warnings and Precautions (5.12)].
Maintenance Treatment
The efficacy of Oleptro for the maintenance treatment of MDD has not been evaluated. While there is no body of evidence available to answer the question of how long a patient treated with Oleptro should continue the drug, it is generally recommended that treatment be continued for several months after an initial response. Patients should be maintained on the lowest effective dose and be periodically reassessed to determine the continued need for maintenance treatment.
Important Administration Instructions
Oleptro tablets are scored to provide flexibility in dosing.
Oleptro can be swallowed whole or administered as a half tablet by breaking the tablet along the score line. Breaking the tablet in half does not affect the controlled-release properties of the tablet.
In order to maintain its controlled-release properties, Oleptro should not be chewed or crushed.
