Multitrace-4 Neonatal Dosage

The suggested dosage ranges for the four trace elements in neonates and pediatric patients are:

ZINC: For full term infants and children up to 5 years of age, 100 mcg zinc/kg/day is recommended. For premature infants up to 3 kg in body weight, 300 mcg zinc/kg/day is suggested.

COPPER: For pediatric patients, the suggested additive dosage level is 20 mcg copper/kg/day.

MANGANESE: For pediatric patients, a dosage of 2 to 10 mcg manganese/kg/day is suggested.

CHROMIUM: For pediatric patients, the suggested additive dosage 0.14 to 0.20 mcg chromium/kg/day.

Periodic monitoring of plasma levels of Zinc, Copper, Manganese and Chromium is suggested as a guideline preparation.

Aseptic addition of MULTITRACE® - 4 NEONATAL to parenteral nutrition solutions under a laminar flow hood is recommended. The trace elements present in the MULTITRACE® - 4 NEONATAL are physically compatible with the electrolytes and vitamins usually present in parenteral nutrition formulations.

Do not directly mix ascorbic acid injection with copper or selenium containing parenteral products in the same syringe or vial, as this admixture may cause the formation of an insoluble precipitate.

Parenteral drug products should be visually inspected for particulate matter and discoloration prior to administration, whenever solution and container permit.