Miglustat Dosage
This dosage information may not include all the information needed to use Miglustat safely and effectively. See additional information for Miglustat.
The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.
Usual Adult Dose for:
Additional dosage information:
Usual Adult Dose for Gaucher Disease
Initial dose: 100 mg orally 3 times a day at regular intervals
Renal Dose Adjustments
CrCl 50 to 70 mL/min: 100 mg twice a day
CrCl 30 to 50 mL/min: 100 mg once a day
CrCl less than 30 mL/min: Not recommended
Liver Dose Adjustments
Data not available
Dose Adjustments
Reductions to 100 mg once or twice daily may be desired in patients experiencing adverse effects, such as diarrhea or tremor.
Precautions
Safety and effectiveness have not been established in pediatric patients (less than 18 years of age).
Dialysis
Data not available
Other Comments
Therapy should be directed by physicians who are knowledgeable in the management of Gaucher disease.
