Gallium Ga 68 Dotatate Dosage

Usual Adult Dose for Diagnostic

After reconstitution with Ga 68-choride, administer 2 MBq/kg (0.054 mCi/kg) by intravenous bolus injection

Comments:

• Verify the injected radioactivity by measuring the radioactivity of the vial containing the Ga 68-dotatate injection with a dose calibrator before administration to the patient.
• Ensure that the injected radioactivity is within 10% of the recommended dose.

Use: For use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs)

Usual Pediatric Dose for Diagnostic

After reconstitution with Ga 68-choride, administer 2 MBq/kg (0.054 mCi/kg) by intravenous bolus injection

Comments:

• Verify the injected radioactivity by measuring the radioactivity of the vial containing the Ga 68-dotatate injection with a dose calibrator before administration to the patient.
• Ensure that the injected radioactivity is within 10% of the recommended dose.
• The safety profile of this drug is similar in adult and pediatric patients with somatostatin receptor positive tumors.

Use: For use with positron emission tomography (PET) for localization of somatostatin receptor positive neuroendocrine tumors (NETs)

Renal Dose Adjustments

Data not available

Liver Dose Adjustments

Data not available

Precautions

Consult WARNINGS section for additional precautions.

Dialysis

Data not available

Other Comments

Administration advice:

• After reconstitution and radiolabeling, handle the Ga 68-dotatate injection with appropriate safety measures to minimize radiation exposure.
• Use waterproof gloves, effective radiation shielding and appropriate safety measures when preparing and handling Ga 68-dotatate injection.
• Instruct patients to drink a sufficient amount of water to ensure adequate hydration prior to administration of this drug, during the first hours following administration and to void frequently.
• This drug is approved for use by a specialist under license by the Nuclear Regulatory Commission or the relevant regulatory authority of an Agreement State.
• The manufacturer product information should be consulted for additional instructions.

Storage requirements: Store in its original packaging at room temperature below 25C (do not freeze). After reconstitution and radiolabeling keep the injection upright with an appropriate shielding to protect from radiation, at a temperature below 25 °C (do not freeze), and for a maximum of 4 hours.

Reconstitution/preparation techniques: The manufacturer product information should be consulted.

General: This drug should be used by or under the control of physicians qualified by specific training and experience in the safe use and handling of radionuclides, and whose experience and training have been approved by the appropriate governmental agency authorized to license the use of radionuclides.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer