Diltiazem / Enalapril Dosage

This dosage information may not include all the information needed to use Diltiazem / Enalapril safely and effectively. See additional information for Diltiazem / Enalapril.

The information at Drugs.com is not a substitute for medical advice. ALWAYS consult your doctor or pharmacist.

Usual Adult Dose for:

Additional dosage information:

Usual Adult Dose for Hypertension

Initial dose: 1 tablet (diltiazem 180 mg/enalapril 5 mg) orally once a day.
Maintenance dose: 1 to 2 tablets (diltiazem 180 mg/enalapril 5 mg) orally in 1 to 2 divided doses.

Renal Dose Adjustments

Because enalapril is primarily eliminated by the kidneys, higher doses are not recommended in patients with renal disease.

Liver Dose Adjustments

Because diltiazem is primarily eliminated by the liver, higher doses are not recommended in patients with liver disease.

Dialysis

Diltiazem does not appear to be removed by peritoneal or hemodialysis.

Enalapril is removed by hemodialysis (20% to 50%).

Other Comments

It is usually appropriate to begin therapy with diltiazem-enalapril only after a patient has failed to achieve the desired antihypertensive effect with either drug alone at maximally recommended doses. It may also be used if the dose of one drug by itself cannot be increased further because of dose-limiting side effects.

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